TRIFLUORO METHYLTHIOMETHYL BENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME

Title:

TRIFLUORO METHYLTHIOMETHYL BENZENE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME

Document Type and Number:

WIPO Patent Application WO/1999/062874

Kind Code:

A1

Abstract:

A process for producing highly pure trifluoro methylthiomethyl benzene derivatives, which are useful as intermediates in synthesizing drugs and pesticides, at a high yield by using readily available materials without resort to flon. This method comprises treating a halogenated benzyl derivative represented by general formula (1), with thiophosgene and potassium fluoride to give a trifluoro methylthiomethyl benzene derivative represented by general formula (2), wherein R represents halogeno, cyano, nitro, benzoyl, etc.; n is an integer of 1 to 5; and X represents halogeno, alkylsulfonyloxy, arylsulfonyloxy, etc.

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Inventors:

KIMURA YOSHIKAZU (JP)
HIYOSHI HIDETAKA (JP)
TORIYABE KEIJI (JP)
WADA NOBUHIDE (JP)

Application Number:

PCT/JP1999/002884

Publication Date:

December 09, 1999

Filing Date:

May 31, 1999

Export Citation:

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Assignee:

IHARA CHEMICAL IND CO (JP)
KUMIAI CHEMICAL INDUSTRY CO (JP)
KIMURA YOSHIKAZU (JP)
HIYOSHI HIDETAKA (JP)
TORIYABE KEIJI (JP)
WADA NOBUHIDE (JP)

International Classes:

C07C319/14; C07C323/07; C07C323/22; C07C323/56; C07C323/60; (IPC1-7): C07C319/14; C07C323/22; C07C323/60

Foreign References:

JPH08295663A	1996-11-12
JPH093038A	1997-01-07

Other References:

SHEPPARD W A: "SUBSTITUTED METHYL GROUPS SUBSTITUENT EFFECTS", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 27, 1 January 1971 (1971-01-01), AMSTERDAM, NL, pages 945 - 951, XP002919459, ISSN: 0040-4020, DOI: 10.1016/S0040-4020(01)92493-7
See also references of EP 1000933A4

Attorney, Agent or Firm:

Kobayashi, Masato (Kagurazaka 4-chome Shinjuku-ku Tokyo, JP)

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