Title:
TRISPECIFIC ANTIBODY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/012457
Kind Code:
A1
Abstract:
The present invention relates to a trispecific antibody specifically binding to CD19, CD3, and CD28, which trispecific antibody contains a fragment derived from an IgD hinge region as a linker. The present invention also relates to the use of the trispecific antibody for treating tumors such as malignant hematological tumors.
Inventors:
CHEN LI (CN)
QIAN WENJING (CN)
ZHU HUAXING (CN)
QIAN WENJING (CN)
ZHU HUAXING (CN)
Application Number:
PCT/CN2023/106817
Publication Date:
January 18, 2024
Filing Date:
July 11, 2023
Export Citation:
Assignee:
CYTOCARES SHANGHAI INC (CN)
International Classes:
C07K14/46; A61K39/395; A61P35/00; A61P35/02; C07K14/435; C12N15/13; C12N15/85
Domestic Patent References:
| WO2021231655A1 | 2021-11-18 | |||
| WO2022072538A1 | 2022-04-07 |
Foreign References:
| CN106589129A | 2017-04-26 | |||
| US20070237779A1 | 2007-10-11 | |||
| CN110520444A | 2019-11-29 | |||
| CN114173810A | 2022-03-11 | |||
| CN115724986A | 2023-03-03 | |||
| CN113286821A | 2021-08-20 |
Attorney, Agent or Firm:
SHANGHAI DIANSHI PARTNERS, P.C. (CN)
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