TRPV4 ACTIVITY INHIBITOR

WIPO Patent Application WO/2020/075764

A1

Provided is a compound that inhibits the activity of TRPV4, and that is useful in the prevention or amelioration of overactive bladder, irritable bowel syndrome, and the like.　This TRPV4 activity inhibitor comprises, as an active ingredient, a rosmarinic acid derivative selected from formulas (Ia)-(Id), or a salt thereof.

WO/2001/047508	COMBINATION OF TRIMEBUTINE WITH AN OPIOID ANALGESIC
JP4224566	Inflammatory cytokine production release inhibitor
JP2008044886	NES-CONTAINING PROTEIN NUCLEAR EXPORT INHIBITOR AND USE THEREOF

IWASHITA MASAZUMI (JP)
KITAMURA NAOYA (JP)

PCT/JP2019/039851

April 16, 2020

October 09, 2019

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KAO CORP (JP)

A61K31/222; A23L33/10; A61P1/00; A61P13/10; A61P43/00; C07C69/732; C07C69/736

JP2018177738A	2018-11-15
JP2005272362A	2005-10-06
JP2005526040A	2005-09-02
JP2003521511A	2003-07-15
JP2014024809A	2014-02-06
JP2005272362A	2005-10-06

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See also references of EP 3865129A4

THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)

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