Title:
A TRUNCATED PROTEIN AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/002062
Kind Code:
A1
Abstract:
Provided is a TRIM72 truncated protein, comprising the Coiled-PRYSPRY domain or PRYSPRY domain or its functional fragment of a TRIM72 protein. Further provided is the use of the TRIM72 truncated protein.
Inventors:
JIA YICHANG (CN)
GUO WEI (CN)
PENG LIN (CN)
GUO WEI (CN)
PENG LIN (CN)
Application Number:
PCT/CN2023/102720
Publication Date:
January 04, 2024
Filing Date:
June 27, 2023
Export Citation:
Assignee:
SINEUGENE THERAPEUTICS CO LTD (CN)
International Classes:
C07K14/47; A61K38/17; A61P9/10; C12N15/10
Foreign References:
| US20190153406A1 | 2019-05-23 | |||
| CN113292658A | 2021-08-24 | |||
| US20150110778A1 | 2015-04-23 | |||
| CN108473546A | 2018-08-31 |
Other References:
DATABASE Protein 1 December 2020 (2020-12-01), ANONYMOUS : "Chain A, Tripartite motif-containing protein 72", XP093124105, retrieved from NCBI Database accession no. 3KB5_A
PALEO,B.J. ET AL.: "Enhancing membrane repair increases regeneration in a sciatic injury model", PLOS ONE, vol. 15, no. 4, 9 April 2020 (2020-04-09), XP093119214, DOI: 10.1371/journal.pone.0231194
DATABASE Protein 18 April 2022 (2022-04-18), ANONYMOUS : "tripartite motif-containing protein 72 [Homo sapiens] ", XP093124107, retrieved from NCBI Database accession no. NP_001008275.2
PARK EUN YOUNG, KWON OH‐BONG, JEONG BYUNG‐CHEON, YI JAE‐SUNG, LEE CHANG SEOK, KO YOUNG‐GYU, SONG HYUN KYU: "Crystal structure of PRY‐SPRY domain of human TRIM72", PROTEINS: STRUCTURE, FUNCTION, AND BIOINFORMATICS, JOHN WILEY & SONS, INC., US, vol. 78, no. 3, 15 February 2010 (2010-02-15), US , pages 790 - 795, XP093124108, ISSN: 0887-3585, DOI: 10.1002/prot.22647
PALEO,B.J. ET AL.: "Enhancing membrane repair increases regeneration in a sciatic injury model", PLOS ONE, vol. 15, no. 4, 9 April 2020 (2020-04-09), XP093119214, DOI: 10.1371/journal.pone.0231194
DATABASE Protein 18 April 2022 (2022-04-18), ANONYMOUS : "tripartite motif-containing protein 72 [Homo sapiens] ", XP093124107, retrieved from NCBI Database accession no. NP_001008275.2
PARK EUN YOUNG, KWON OH‐BONG, JEONG BYUNG‐CHEON, YI JAE‐SUNG, LEE CHANG SEOK, KO YOUNG‐GYU, SONG HYUN KYU: "Crystal structure of PRY‐SPRY domain of human TRIM72", PROTEINS: STRUCTURE, FUNCTION, AND BIOINFORMATICS, JOHN WILEY & SONS, INC., US, vol. 78, no. 3, 15 February 2010 (2010-02-15), US , pages 790 - 795, XP093124108, ISSN: 0887-3585, DOI: 10.1002/prot.22647
Attorney, Agent or Firm:
SHANGHAI DIANSHI PARTNERS , P.C. et al. (CN)
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