Title:
TUMOR TREATMENT OR PREVENTION METHOD
Document Type and Number:
WIPO Patent Application WO/2024/088379
Kind Code:
A1
Abstract:
Disclosed is a tumor treatment or prevention method. The method comprises: administering, to an individual in need of the method, a therapeutically or prophylactically effective amount of a compound represented by general formula (I), or a pharmaceutically acceptable salt thereof: general formula (I), wherein R1, R2, X and Y are as defined in the present disclosure.
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Inventors:
HUANG YONG (CN)
JIANG CHENRAN (CN)
CHEN XUEMING (CN)
CHEN JIEAN (CN)
LIU YUN (CN)
AN YUAN (CN)
WU GUANLIN (CN)
JIANG CHENRAN (CN)
CHEN XUEMING (CN)
CHEN JIEAN (CN)
LIU YUN (CN)
AN YUAN (CN)
WU GUANLIN (CN)
Application Number:
PCT/CN2023/127066
Publication Date:
May 02, 2024
Filing Date:
October 27, 2023
Export Citation:
Assignee:
UNIV HONG KONG SCIENCE & TECH (CN)
PINGSHAN TRANSLATIONAL MEDICINE CENTER SHENZHEN BAY LABORATORY (CN)
PINGSHAN TRANSLATIONAL MEDICINE CENTER SHENZHEN BAY LABORATORY (CN)
International Classes:
A61K31/519; A61P35/00; C07D471/04
Domestic Patent References:
| WO2004085425A1 | 2004-10-07 | |||
| WO2006017443A2 | 2006-02-16 | |||
| WO2008016192A2 | 2008-02-07 |
Foreign References:
| US20130096136A1 | 2013-04-18 |
Other References:
MICHELE H POTASHMAN, JAMES BREADY, ANGELA COXON, THOMAS M DEMELFI, LUCIAN DIPIETRO, NICHOLAS DOERR, DANIEL ELBAUM, JUAN ESTRADA, P: "Design, synthesis, and evaluation of orally active benzimidazoles and benzoxazoles as vascular endothelial growth factor-2 receptor tyrosine kinase inhibitors", JOURNAL OF MEDICINAL CHEMISTRY, UNITED STATES, 6 September 2007 (2007-09-06), United States , pages 4351 - 4373, XP055135231, Retrieved from the Internet DOI: 10.1021/jm070034i
RUAN, ZHIHUA ET AL.: "Pseudo Receptor Probes: A Novel Pseudo Receptor-based QSAR Method and Application into Studies on a New Kind of Selective Vascular Endothelial Growth Factor-2 Receptor Inhibitors", CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, vol. 92, no. 2, 8 March 2008 (2008-03-08), pages 157 - 168, XP022678586, DOI: 10.1016/j.chemolab.2008.02.007
RUAN, ZHIHUA ET AL.: "Pseudo Receptor Probes: A Novel Pseudo Receptor-based QSAR Method and Application into Studies on a New Kind of Selective Vascular Endothelial Growth Factor-2 Receptor Inhibitors", CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, vol. 92, no. 2, 8 March 2008 (2008-03-08), pages 157 - 168, XP022678586, DOI: 10.1016/j.chemolab.2008.02.007
Attorney, Agent or Firm:
BEIJING HARTEND INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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