Title:
ULTRASOUND-GUIDED DRUG-LOADED MICROBUBBLE DELIVERY METHOD AND APPARATUS
Document Type and Number:
WIPO Patent Application WO/2021/258762
Kind Code:
A1
Abstract:
An ultrasound-guided drug-loaded microbubble delivery method and apparatus, and an electronic device and a computer-readable storage medium. The method comprises: step 110, sending a first ultrasound wave signal by using an array transducer, so as to destroy a drug-loaded microbubble in the current destruction area; step 120, sending a second ultrasound wave signal by using the array transducer, so as to acquire an ultrasound image; step 130, identifying a blood vessel contour of the destruction area according to the ultrasound image; and step 140, updating feature parameters of the destruction area according to the blood vessel contour. In the method, since a destruction area is updated in real time according to a blood vessel contour, the precision of destroying a drug-loaded microbubble is improved, such that the delivery effect of the drug-loaded microbubble is better; and by continuously updating the parameters of the destruction area, the destruction area is always kept within a blood vessel, thereby preventing unnecessary tissue damage caused by transmitting an ultrasound wave signal to tissue around the blood vessel, and also shortening the delivery time of the drug-loaded microbubble.
Inventors:
GUO WENYU (CN)
AN JIAN (CN)
DONG FEIHONG (CN)
HUANG SHUO (CN)
ZHANG JUE (CN)
AN JIAN (CN)
DONG FEIHONG (CN)
HUANG SHUO (CN)
ZHANG JUE (CN)
Application Number:
PCT/CN2021/078155
Publication Date:
December 30, 2021
Filing Date:
February 26, 2021
Export Citation:
Assignee:
NANJING TRANSCEND VIVOSCOPE BIO TECH CO LTD (CN)
International Classes:
A61B8/00; A61M37/00; A61N7/00
Domestic Patent References:
| WO2012030675A1 | 2012-03-08 |
Foreign References:
| CN111729188A | 2020-10-02 | |||
| US20130046179A1 | 2013-02-21 | |||
| CN110339494A | 2019-10-18 | |||
| US20200077982A1 | 2020-03-12 | |||
| US20050084538A1 | 2005-04-21 |
Other References:
See also references of EP 4059438A4
Attorney, Agent or Firm:
BEIJING BRIGHT IP AGENCY CO., LTD. (CN)
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