Title:
UREA DERIVATIVE FOR USE IN QUANTIFICATION OF HYDROGEN PEROXIDE
Document Type and Number:
WIPO Patent Application WO/2008/047655
Kind Code:
A1
Abstract:
Disclosed is a novel substance which has excellent solubility and stability in an aqueous solution corresponding to a biological liquid sample and can be suitably used as a clinical reagent for quantifying hydrogen peroxide in the presence of a peroxidase. Specifically disclosed is an urea derivative represented by the formula (I) [wherein R1 represents an atomic group represented by the formula (II); R2 and R3 independently represent a 4-disubstituted aminoaryl group, provided the aryl group in R2 and the aryl group in R3 may be linked to each other through a sulfur or oxygen atom, and at least one site in the aryl group in each of R2 and R3 may be substituted by a sulfonate group; n represents an integer of 1 to 4; and X represents a hydrogen, sodium or potassium atom].
Inventors:
NOGUCHI KATSUYA (JP)
WATANABE EIJI (JP)
ISHIYAMA MUNETAKA (JP)
WATANABE EIJI (JP)
ISHIYAMA MUNETAKA (JP)
Application Number:
PCT/JP2007/069799
Publication Date:
April 24, 2008
Filing Date:
October 11, 2007
Export Citation:
Assignee:
DOJINDO LAB (JP)
NOGUCHI KATSUYA (JP)
WATANABE EIJI (JP)
ISHIYAMA MUNETAKA (JP)
NOGUCHI KATSUYA (JP)
WATANABE EIJI (JP)
ISHIYAMA MUNETAKA (JP)
International Classes:
C07C309/15; C07D279/30; C12Q1/28
Foreign References:
| JPS63246356A | 1988-10-13 | |||
| JPH01128797A | 1989-05-22 | |||
| JPH06289015A | 1994-10-18 |
Attorney, Agent or Firm:
TSUTSUI, Satoru et al. (3-30-15 Hakataekimae,Hakata-ku, Fukuoka-shi, Fukuoka, JP)
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