Title:
USE OF ANTAGONISTS OF EGF OR TGF-ALPHA FOR THE TREATMENT AND PROPHYLAXIS OF ACNE
Document Type and Number:
WIPO Patent Application WO1995024896
Kind Code:
A3
Abstract:
Compositions comprising one or more antagonists of EGF, TGF- alpha or EGF-receptor function for use in treating acne, spots and pimples are described.
Inventors:
EVENSON ALAN
GIBSON WALTER THOMAS
GREEN MARTIN RICHARD
GUY ROBERT
KEALEY TERENCE GEORGE EVELYN
GIBSON WALTER THOMAS
GREEN MARTIN RICHARD
GUY ROBERT
KEALEY TERENCE GEORGE EVELYN
Application Number:
PCT/EP1995/000877
Publication Date:
November 09, 1995
Filing Date:
March 08, 1995
Export Citation:
Assignee:
UNILEVER PLC (GB)
UNILEVER NV (GB)
UNILEVER NV (GB)
International Classes:
A61K8/30; A61K8/00; A61K8/31; A61K8/33; A61K8/34; A61K8/35; A61K8/36; A61K8/368; A61K8/40; A61K8/42; A61K8/46; A61K8/99; A61K31/047; A61K31/165; A61K31/19; A61K31/275; A61K39/395; A61K45/00; A61P17/00; A61Q19/00; A61Q19/02; (IPC1-7): A61K31/165; A61K31/19; A61K31/275
Domestic Patent References:
| WO1988003805A1 | 1988-06-02 | |||
| WO1991016892A1 | 1991-11-14 | |||
| WO1992006946A1 | 1992-04-30 | |||
| WO1992017206A1 | 1992-10-15 |
Foreign References:
| EP0586002A2 | 1994-03-09 |
Other References:
DATABASE WPI Week 8712, Derwent World Patents Index; AN 87-084155
DATABASE WPI Week 9244, Derwent World Patents Index; AN 92-363064
DATABASE WPI Week 9336, Derwent World Patents Index; AN 93-285353
DATABASE WPI Week 9321, Derwent World Patents Index; AN 93-172621
SUMMERLY R ET AL: "The in vitro incorporation of 14 C-acetate into the isolated sebaceous glands and appendage-freed epidermis of human skin. A technique for the study of lipid synthesis in the isolated sebaceous gland.", BR J DERMATOL, NOV 1971, 85 (5) P424-31, ENGLAND
GUY, R. ET AL: "Isolation and maintenace of the human pilosebaceous duct: 13-cis retinoic acid acts directly on the duct in vitro", BRITISH JOURNAL OF DERMATOLOGY, vol. 128, no. 3, pages 242 - 248
DATABASE WPI Week 9244, Derwent World Patents Index; AN 92-363064
DATABASE WPI Week 9336, Derwent World Patents Index; AN 93-285353
DATABASE WPI Week 9321, Derwent World Patents Index; AN 93-172621
SUMMERLY R ET AL: "The in vitro incorporation of 14 C-acetate into the isolated sebaceous glands and appendage-freed epidermis of human skin. A technique for the study of lipid synthesis in the isolated sebaceous gland.", BR J DERMATOL, NOV 1971, 85 (5) P424-31, ENGLAND
GUY, R. ET AL: "Isolation and maintenace of the human pilosebaceous duct: 13-cis retinoic acid acts directly on the duct in vitro", BRITISH JOURNAL OF DERMATOLOGY, vol. 128, no. 3, pages 242 - 248
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