Title:
USE OF ANTIOXIDANTS TO TREAT BONE LOSS DISORDERS
Document Type and Number:
WIPO Patent Application WO2004093995
Kind Code:
A3
Abstract:
Bone loss disorders can be treated or prevented by administration of an agent which increases the levels of oxidant defences and/or at least one antioxidant in a subject. The agent can be an antioxidant and may act either directly to increase antioxidant levels and/or oxidant defences or indirectly.
Inventors:
CHAMBERS TIMOTHY JOHN (GB)
FULLER KAREN (GB)
JAGGER CHRISTOPHER JOHN (GB)
LEAN JENNY MAREE (GB)
FULLER KAREN (GB)
JAGGER CHRISTOPHER JOHN (GB)
LEAN JENNY MAREE (GB)
Application Number:
PCT/GB2004/001695
Publication Date:
April 21, 2005
Filing Date:
April 19, 2004
Export Citation:
Assignee:
ST GEORGES ENTPR LTD (GB)
CHAMBERS TIMOTHY JOHN (GB)
FULLER KAREN (GB)
JAGGER CHRISTOPHER JOHN (GB)
LEAN JENNY MAREE (GB)
CHAMBERS TIMOTHY JOHN (GB)
FULLER KAREN (GB)
JAGGER CHRISTOPHER JOHN (GB)
LEAN JENNY MAREE (GB)
International Classes:
A61K31/00; A61K31/05; A61K31/07; A61K31/10; A61K31/122; A61K31/195; A61K31/352; A61K31/355; A61K31/375; A61K31/385; A61K31/444; A61K31/455; A61K31/497; A61K45/06; A61P9/10; G01N33/50; (IPC1-7): A61P9/10; A61K31/05; A61K31/07; A61K31/10; A61K31/122; A61K31/195; A61K31/352; A61K31/355; A61K31/375; A61K31/385; A61K31/444; A61K31/455; A61K31/497
Foreign References:
| US20020048798A1 | 2002-04-25 | |||
| EP1214893A1 | 2002-06-19 | |||
| CA2012208C | 2001-05-22 | |||
| US4590067A | 1986-05-20 | |||
| EP1431385A1 | 2004-06-23 |
Other References:
PATENT ABSTRACTS OF JAPAN vol. 0183, no. 47 (C - 1219) 30 June 1994 (1994-06-30)
NAKAMUTA HIROMICHI ET AL: "A novel bone-protective effect of taurine on low Ca diet-induced osteoporosis in rats", JAPANESE JOURNAL OF PHARMACOLOGY, vol. 88, no. Supplement 1, 2002, & 75TH ANNUAL MEETING OF THE JAPANESE PHARMACOLOGICAL SOCIETY; KUMAMOTO, JAPAN; MARCH 13-15, 2002, pages 108P, XP009034443, ISSN: 0021-5198
HALL T J ET AL: "THE ROLE OF REACTIVE OXYGEN INTERMEDIATES IN OSTEOCLASTIC BONE RESORPTION", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 207, no. 1, 6 February 1995 (1995-02-06), pages 280 - 287, XP002068360, ISSN: 0006-291X
PATENT ABSTRACTS OF JAPAN vol. 1999, no. 10 31 August 1999 (1999-08-31)
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 07 31 July 1996 (1996-07-31)
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 06 28 June 1996 (1996-06-28)
DATABASE EMBASE [online] ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL; 1994, HANIOKA T ET AL: "Effect of topical application of Coenzyme Q10 on adult periodontitis", XP002291089, Database accession no. EMB-1995041314
NAKAMUTA HIROMICHI ET AL: "A novel bone-protective effect of taurine on low Ca diet-induced osteoporosis in rats", JAPANESE JOURNAL OF PHARMACOLOGY, vol. 88, no. Supplement 1, 2002, & 75TH ANNUAL MEETING OF THE JAPANESE PHARMACOLOGICAL SOCIETY; KUMAMOTO, JAPAN; MARCH 13-15, 2002, pages 108P, XP009034443, ISSN: 0021-5198
HALL T J ET AL: "THE ROLE OF REACTIVE OXYGEN INTERMEDIATES IN OSTEOCLASTIC BONE RESORPTION", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 207, no. 1, 6 February 1995 (1995-02-06), pages 280 - 287, XP002068360, ISSN: 0006-291X
PATENT ABSTRACTS OF JAPAN vol. 1999, no. 10 31 August 1999 (1999-08-31)
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 07 31 July 1996 (1996-07-31)
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 06 28 June 1996 (1996-06-28)
DATABASE EMBASE [online] ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL; 1994, HANIOKA T ET AL: "Effect of topical application of Coenzyme Q10 on adult periodontitis", XP002291089, Database accession no. EMB-1995041314
Download PDF: