Title:
USE OF CCL26
Document Type and Number:
WIPO Patent Application WO/2023/137944
Kind Code:
A1
Abstract:
A use of CCL26. Different antigen proteins are delivered to the surfaces of DC cells by utilizing a chemotactic binding capacity of CCL26 to surface receptors of immune cells such as the DC cells, so that the efficiency of phagocytosis, processing and presentation of different antigen proteins by the DC cells is improved, and the effect of preventing and treating related diseases is improved by further adding a T2 sequence into an antigen. The T2 sequence has a very strong immunological enhancement effect by means of experimental determination, and can further excite body fluid and cellular immune response in the process of promoting antigen presentation, thereby finally achieving the effect of inhibiting related tumor growth.
More Like This:
| WO/2003/093314 | CONNECTIVE TISSUE STIMULATING PEPTIDES |
| JP2007105044 | MODIFIED PEPTIDE AS THERAPEUTIC AGENT |
| JP2024512714 | Fusion proteins, pharmaceutical compositions, and therapeutic applications |
Inventors:
JIANG JIANDONG (CN)
WU TINGXIN (CN)
QI HAILONG (CN)
LI YUHUAN (CN)
ZHANG JINLAN (CN)
YAO YANLING (CN)
WANG XUDONG (CN)
XIE HUANGFAN (CN)
LIU DEFANG (CN)
WANG XIAOFANG (CN)
SUN ZHONGJIE (CN)
WU TINGXIN (CN)
QI HAILONG (CN)
LI YUHUAN (CN)
ZHANG JINLAN (CN)
YAO YANLING (CN)
WANG XUDONG (CN)
XIE HUANGFAN (CN)
LIU DEFANG (CN)
WANG XIAOFANG (CN)
SUN ZHONGJIE (CN)
Application Number:
PCT/CN2022/097089
Publication Date:
July 27, 2023
Filing Date:
June 06, 2022
Export Citation:
Assignee:
NEWISH TECH BEIJING CO LTD (CN)
INST MED BIOTECHNOLOGY CAMS (CN)
INST MED BIOTECHNOLOGY CAMS (CN)
International Classes:
C07K19/00; A61K39/12; A61K39/39; C12N5/10; C12N15/62
Domestic Patent References:
| WO2019238022A1 | 2019-12-19 | |||
| WO2021194826A2 | 2021-09-30 |
Foreign References:
| CN114106207A | 2022-03-01 | |||
| CN114573716A | 2022-06-03 | |||
| CN113150083A | 2021-07-23 | |||
| CN107375919A | 2017-11-24 | |||
| CN112930192A | 2021-06-08 | |||
| JP2018052953A | 2018-04-05 | |||
| CN103857406A | 2014-06-11 |
Other References:
YANG, XINZHEN ET AL.: "Highly Stable Trimers Formed by Human Immunodeficiency Virus Type 1 Envelope Glycoproteins Fused with the Trimeric Motif of T4 Bacteriophage Fibritin.", JOURNAL OF VIROLOGY., vol. 76, no. 9, 31 May 2002 (2002-05-31), XP002321404, DOI: 10.1128/JVI.76.9.4634-4642.2002
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
Download PDF:
Previous Patent: TWO-STATE FLOW DIVISION PROLONGING AND CONTACTING TYPE WASTE LIQUID FILTERING AND SAMPLING DEVICE FO...
Next Patent: USE OF CXCL14
Next Patent: USE OF CXCL14