USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS

Title:

USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS

Document Type and Number:

WIPO Patent Application WO2004000801

Kind Code:

A3

Abstract:

The present invention provides methods of inducing contraception which includes delivering to a female a composition containing a compound of formula I, formula II, or tautomers thereof, in a regimen which involves delivering one or more of a selective estrogen receptor modulator, wherein formula I is: (I) and wherein R<1>-R<5> and Q<1> are defined as described herein. Methods of providing hormone replacement therapy and for treating carcinomas, dysfunctional bleeding, uterine leiomyomata, endometriosis, and polycystic ovary syndrome is provided which includes delivering a compound of formula I or formula II and a selective estrogen receptor modulator are also described.

Inventors:

FENSOME ANDREW (US)
GRUBB GARY (US)
HARRISON DIANE DEBORAH (US)
WINNEKER RICHARD CRAIG (US)
ZHANG PUWEN (US)
KERN JEFFREY CURTIS (US)
TEREFENKO EUGENE ANTHONY (US)

Application Number:

PCT/US2003/019751

Publication Date:

March 25, 2004

Filing Date:

June 23, 2003

Export Citation:

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Assignee:

WYETH CORP (US)
FENSOME ANDREW (US)
GRUBB GARY (US)
HARRISON DIANE DEBORAH (US)
WINNEKER RICHARD CRAIG (US)
ZHANG PUWEN (US)
KERN JEFFREY CURTIS (US)
TEREFENKO EUGENE ANTHONY (US)

International Classes:

A61K31/426; A61K31/536; A61K31/537; A61K45/00; A61K31/54; A61K31/554; A61K31/565; A61P5/28; A61P5/30; A61P7/04; A61P15/00; A61P15/12; A61P15/18; A61P35/00; A61P43/00; (IPC1-7): A61K31/535; A61K31/265; A61K31/16

Domestic Patent References:

WO2000066570A1

2000-11-09

Other References: