USE OF DESLORATADINE FOR TREATING ALLERGIC AND INFLAMMATORY CONDITIONS

WIPO Patent Application WO2001021161

A3

The use of desloratadine for the preparation of a medicament for treating and/or preventing allergic and inflammatory conditions of the skin or upper and lower airway passages in a human while avoiding the food effect associated with non-sedating antihistamines, e.g., loratadine or fexofenadine is disclosed.

AFFRIME MELTON B (US)
BANFIELD CHRISTOPHER R (US)
GUPTA SAMIR K (US)
PADHI DESMOND (US)

PCT/US2000/025595

January 17, 2002

September 19, 2000

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SCHERING CORP (US)
AFFRIME MELTON B (US)
BANFIELD CHRISTOPHER R (US)
GUPTA SAMIR K (US)
PADHI DESMOND (US)

A61K31/4545; A61P27/16; A61P29/00; A61P37/00; (IPC1-7): A61K31/4545; A61P37/08

US5595997A	1997-01-21
US5900421A	1999-05-04
US4659716A	1987-04-21

NOMEIR AMIN A ET AL: "Influence of food on the oral bioavailability of loratadine and pseudoephedrine from extended-release tablets in healthy volunteers", JOURNAL OF CLINICAL PHARMACOLOGY, LIPPINCOTT CO, HAGERSTOWN, MD, US, vol. 36, 1996, pages 923 - 930, XP000926410, ISSN: 0091-2700
SALMUN L M ET AL: "EFFICACY AND SAFETY OF DESLORATADINE IN SEASONAL ALLERGIC RHINITIS", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, MOSBY - YEARLY BOOK, INC, US, vol. 105, no. 1, PART 2, January 2000 (2000-01-01), pages 5384 - 5385, XP001000942, ISSN: 0091-6749
GUPTA, S.; PADHI, D. ET AL: "The effect of food on the oral bioavailability of desloratadine", THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 105, no. 1, January 2000 (2000-01-01), pages S386 - S387, XP001016245

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