THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA

Title:

THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA

Document Type and Number:

WIPO Patent Application WO/2016/112874

Kind Code:

A1

Abstract:

Disclosed are uses of 3,3',5,5'-tetraisopropyl-4,4'-diphenol, pharmaceutical salts thereof, esterification products thereof, or solvates thereof in the preparation of medicines for the prevention and treatment of cerebral ischemia.

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Inventors:

WANG RUTAO (CN)
CHEN TAO (CN)
AN LONG (CN)
ZHAO YI (CN)
WANG WEIJIAO (CN)
GUO SHUPAN (CN)
XIAO SA (CN)
PANG JINGHUA (CN)
HU HUIJING (CN)

Application Number:

PCT/CN2016/076112

Publication Date:

July 21, 2016

Filing Date:

March 11, 2016

Export Citation:

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Assignee:

XI AN LIBANG PHARMACEUTICAL CO LTD (CN)

International Classes:

A61K9/08; A61K31/05; A61K9/107; A61K9/127; A61K9/16; A61K9/19; A61K9/20; A61K9/48; A61K31/222; A61P9/10; A61P25/28; C07C39/15

Foreign References:

CN104546809A	2015-04-29
CN101804043A	2010-08-18
CN104557532A	2015-04-29
JP2015078145A	2015-04-23

Other References:

DONG, T.T.H. ET AL.: "Pre-treatment with the Synthetic Antioxidant T-butyl Bisphenol Protects Cerebral Tissues from Experimental Ischemia Reperfusion Injury", JOURNAL OF NEUROCHEMISTRY, vol. 130, 31 December 2014 (2014-12-31), pages 733 - 747, XP055467271
LEE, Y.E. ET AL.: "Selective Oxidative Homo-and Cross-Coupling of Phenols with Aerobic Catalysts", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 136, 5 May 2014 (2014-05-05), pages 6782 - 6785, XP055467276

Attorney, Agent or Firm:

BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
北京三友知识产权代理有限公司 (CN)

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