Title:
USE OF ERSS-SELECTIVE LIGANDS FOR REGULATING FERTILITY AND COMPOUNDS USEFUL THEREFORE
Document Type and Number:
WIPO Patent Application WO2002068548
Kind Code:
A1
Abstract:
The present invention discloses the use of ERSS-selective ligands for production of medicaments for regulating fertility without additional use of a progestin. ERSS-agonists are used for treatment of infertility and ERSS-antagonists for contraception.
Inventors:
HEGELE-HARTUNG CHRISTA
FRITZEMEIER KARL-HEINRICH
YAMANOUCHI HIROSHI
PETERS OLAF
KOSEMUND DIRK
MUELLER GERD
TORNUS INGO
SCHUBERT GERD
FRITZEMEIER KARL-HEINRICH
YAMANOUCHI HIROSHI
PETERS OLAF
KOSEMUND DIRK
MUELLER GERD
TORNUS INGO
SCHUBERT GERD
Application Number:
PCT/EP2002/002117
Publication Date:
September 06, 2002
Filing Date:
February 27, 2002
Export Citation:
Assignee:
SCHERING AG (DE)
International Classes:
A61K45/00; A61K31/00; A61K31/05; A61K31/122; A61K31/56; A61K45/06; A61P15/08; A61P15/16; A61P15/18; A61P35/00; C07J63/00; (IPC1-7): C09D131/02; C09D5/02; C08J3/02
Domestic Patent References:
| WO2000047603A2 | 2000-08-17 | |||
| WO2000063228A1 | 2000-10-26 |
Foreign References:
| US4578475A | 1986-03-25 |
Other References:
F.LABRIE E.A.: "EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium", JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, vol. 69, no. 1-6, 1999, pages 51 - 84, XP000852985
W.LOTZ: "Biological activities and receptor affinities of some natural and synthetic oestrogens and their D-homo analogues", EXPERIENTIA, vol. 34, no. 10, 1978, pages 1373 - 1374, XP002228748
J.A.KATZENELLENBOGEN: "Exploring the structural space of estrogen receptor ligands: subtype-selective binding and activation", ABSTRACTS OF PAPERS AMERICAN CHEMICAL SOCIETY, vol. 222, no. 1-2, 2001, pages 86, XP008012796
W.LOTZ: "Biological activities and receptor affinities of some natural and synthetic oestrogens and their D-homo analogues", EXPERIENTIA, vol. 34, no. 10, 1978, pages 1373 - 1374, XP002228748
J.A.KATZENELLENBOGEN: "Exploring the structural space of estrogen receptor ligands: subtype-selective binding and activation", ABSTRACTS OF PAPERS AMERICAN CHEMICAL SOCIETY, vol. 222, no. 1-2, 2001, pages 86, XP008012796
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