Title:
USE OF FATTY ACID ELONGASE GENE AND ESTERASE GENE IN SYNTHESIS OF NERVONIC ACID AND GREASE IN YEAST
Document Type and Number:
WIPO Patent Application WO/2022/105841
Kind Code:
A1
Abstract:
Provided is an engineering bacterium for producing nervonic acid and/or grease. The genome of the engineering bacterium is integrated with an expression cassette expressing a protein encoded by 3-ketoacyl-CoA synthase (KCS) gene and/or an esterase gene.
Inventors:
WANG SHIAN (CN)
RUAN JIANCHANG (CN)
LI FULI (CN)
SU HANG (CN)
FAN WEIMING (CN)
HAN XINGFENG (CN)
MENG ZIYUE (CN)
SHI PENGHUI (CN)
RUAN JIANCHANG (CN)
LI FULI (CN)
SU HANG (CN)
FAN WEIMING (CN)
HAN XINGFENG (CN)
MENG ZIYUE (CN)
SHI PENGHUI (CN)
Application Number:
PCT/CN2021/131563
Publication Date:
May 27, 2022
Filing Date:
November 18, 2021
Export Citation:
Assignee:
QINGDAO INST BIOENERGY & BIOPROCESS TECH CAS (CN)
ZHEJIANG ZHENYUAN PHARMACEUTICAL CO LTD (CN)
ZHEJIANG ZHENYUAN PHARMACEUTICAL CO LTD (CN)
International Classes:
C12N1/19; C12P7/64; C12R1/85
Foreign References:
| CN108271383A | 2018-07-10 | |||
| CN103509817A | 2014-01-15 | |||
| CN110358692A | 2019-10-22 | |||
| US20060094086A1 | 2006-05-04 |
Other References:
BAO RIMA: "Construction of Neurogenic Acid Saccharomyces Cerevisiae Cell Strain", MASTER THESIS, TIANJIN POLYTECHNIC UNIVERSITY, CN, 30 September 2018 (2018-09-30), CN , XP055932282, ISSN: 1674-0246
DATABASE NUCLEOTIDE 26 August 2019 (2019-08-26), ANONYMOUS : "PREDICTED: Syzygium oleosum 3-ketoacyl-CoA synthase 11-like (LOC115662539), mRNA", XP055932284, retrieved from NCBI
SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
QIAOSTEPHANOPOULOS, METABOLIC ENGINEERING, vol. 29, 2015, pages 56 - 65
XU ET AL., GIGASCIENCE, vol. 8, 2019, pages 1 - 14
"GenBank", Database accession no. EU871787.1
DATABASE NUCLEOTIDE 26 August 2019 (2019-08-26), ANONYMOUS : "PREDICTED: Syzygium oleosum 3-ketoacyl-CoA synthase 11-like (LOC115662539), mRNA", XP055932284, retrieved from NCBI
SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
QIAOSTEPHANOPOULOS, METABOLIC ENGINEERING, vol. 29, 2015, pages 56 - 65
XU ET AL., GIGASCIENCE, vol. 8, 2019, pages 1 - 14
"GenBank", Database accession no. EU871787.1
Attorney, Agent or Firm:
XU&PARTNERS, LLC. (CN)
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