Title:
USE OF FGFR INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2021/089005
Kind Code:
A1
Abstract:
Provided is the use of an FGFR inhibitor. More specifically, provided are an FGFR inhibitor for treating FGFR-related tumors or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising same, a method for treating FGFR-related tumors by means of using a drug comprising same, and the use thereof in the preparation of a drug for treating FGFR-related tumors. In vitro and in vivo test results show that compound A has the effect of inhibiting the activity of digestive or urinary system tumors related to abnormal FGFR expression, can be used to develop a drug for treating diseases involving digestive or urinary system tumors, and has important clinical application values.
Inventors:
WANG CAIXIA (CN)
WANG LINGLING (CN)
ZHANG YANG (CN)
LI GUIXIA (CN)
QI HUANHUAN (CN)
ZHAO JING (CN)
LI XIAO (CN)
WANG LINGLING (CN)
ZHANG YANG (CN)
LI GUIXIA (CN)
QI HUANHUAN (CN)
ZHAO JING (CN)
LI XIAO (CN)
Application Number:
PCT/CN2020/127211
Publication Date:
May 14, 2021
Filing Date:
November 06, 2020
Export Citation:
Assignee:
CSPC ZHONGQI PHARMACEUTICAL TECH SHIJIAZHUANG CO LTD (CN)
International Classes:
A61K31/53; A61P35/00
Domestic Patent References:
| WO2020164603A1 | 2020-08-20 | |||
| WO2019034076A1 | 2019-02-21 | |||
| WO2019034075A1 | 2019-02-21 | |||
| WO2017215485A1 | 2017-12-21 | |||
| WO2018121650A1 | 2018-07-05 |
Foreign References:
| CN104245700A | 2014-12-24 | |||
| CN103958512A | 2014-07-30 |
Other References:
GAIA CRISTINA GHEDINI; ROBERTO RONCA; MARCO PRESTA; ARIANNA GIACOMINI: "Future applications of FGF/FGFR inhibitors in cancer", EXPERT REVIEW OF ANTICANCER THERAPY, vol. 18, no. 9, 1 January 2018 (2018-01-01), GB, pages 861 - 872, XP009527867, ISSN: 1473-7140, DOI: 10.1080/14737140.2018.1491795
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
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