Title:
USE OF FUCOSAN SULFATE IN PROMOTING FOAM CELL AUTOPHAGY TO DECOMPOSE OX-LDL
Document Type and Number:
WIPO Patent Application WO/2021/147151
Kind Code:
A1
Abstract:
Disclosed is the use of fucosan sulfate in promoting foam cell autophagy to decompose ox-LDL, which falls within the technical field of pharmaceutical preparations. The fucosan sulfate can promote cell autophagy to decompose excessive ox-LDL in foam cells, thereby providing a new direction for the recovery of foam cells to normal macrophages and providing a new idea for the use of fucosan sulfate.
Inventors:
SONG SHULIANG (CN)
JI AIGUO (CN)
JI AIGUO (CN)
Application Number:
PCT/CN2020/079331
Publication Date:
July 29, 2021
Filing Date:
March 13, 2020
Export Citation:
Assignee:
UNIV SHANDONG (CN)
International Classes:
A61K31/737; A61P9/10
Foreign References:
| CN109432121A | 2019-03-08 | |||
| CN108014086A | 2018-05-11 | |||
| CN105399848A | 2016-03-16 |
Other References:
WANG XIN, PEI LILI, LIU HAIBO, QV KAI, XIAN WEIWEI, LIU JIA, ZHANG GUOMIN: "Fucoidan attenuates atherosclerosis in LDLR -/- mice through inhibition of inflammation and oxidative stress", INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, E-CENTURY PUBLISHING CORPORATION, US, vol. 9, no. 7, 15 July 2016 (2016-07-15), US, pages 6896 - 6904, XP055831429, ISSN: 1936-2625
Attorney, Agent or Firm:
JINAN SHENGDA INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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