Title:
USE OF IDHP IN PREPARATION OF DRUG OR HEALTH PRODUCT FOR PREVENTION AND TREATMENT OF CORONARY ATHEROSCLEROSIS DISEASE
Document Type and Number:
WIPO Patent Application WO/2018/064953
Kind Code:
A1
Abstract:
Use of isopropyl β-(3,4-dihydroxyphenyl)-α-hydroxypropionate (IDHP) in the preparation of a drug or a health product for prevention and treatment of coronary atherosclerosis diseases. The IDHP can also be used to inhibit platelet aggregation, to promote angiogenesis, and to prepare a drug and a health product for prevention and treatment of senile vascular dementia.
Inventors:
ZHENG XIAOHUI (CN)
BAI YAJUN (CN)
JIA PU (CN)
ZHANG YAJUN (CN)
LIAO SHA (CN)
BAI YAJUN (CN)
JIA PU (CN)
ZHANG YAJUN (CN)
LIAO SHA (CN)
Application Number:
PCT/CN2017/104278
Publication Date:
April 12, 2018
Filing Date:
September 29, 2017
Export Citation:
Assignee:
UNIV NORTHWEST (CN)
International Classes:
A61K31/216; A61P7/02; A61P9/00; A61P9/10; A61P25/28
Foreign References:
| CN1583710A | 2005-02-23 | |||
| CN106420688A | 2017-02-22 |
Other References:
TIAN, J.W. ET AL.: "a Novel Compound, Ameliorates Cerebral Infarction in Rats by Antioxidant Action", NEUROSCIENCE LETTERS, vol. 442, no. 3, 19 September 2008 (2008-09-19), pages 279 - 283, XP023782949, ISSN: 0304-3940, doi:10.1016/j.neulet.2008.07.033
XIN GU: "THE ASYMMETRIC SYNTHESIS AND PHARMACOLOGICAL STUDIES OF DANSHENSU AND ITS DERIVATIVES", MASTER THESIS, 15 January 2016 (2016-01-15), pages 1 - 58, XP009515625, ISSN: 1674-0246
SHU, JINGJING ET AL.: "Progress on the Pharmacological Actions and Mechanism of Danshensu", JOURNAL OF PHARMACEUTICAL PRACTICE, vol. 30, no. 4, 25 July 2012 (2012-07-25), pages 266 - 268,298, XP009515261, ISSN: 1006-0111
See also references of EP 3524241A4
XIN GU: "THE ASYMMETRIC SYNTHESIS AND PHARMACOLOGICAL STUDIES OF DANSHENSU AND ITS DERIVATIVES", MASTER THESIS, 15 January 2016 (2016-01-15), pages 1 - 58, XP009515625, ISSN: 1674-0246
SHU, JINGJING ET AL.: "Progress on the Pharmacological Actions and Mechanism of Danshensu", JOURNAL OF PHARMACEUTICAL PRACTICE, vol. 30, no. 4, 25 July 2012 (2012-07-25), pages 266 - 268,298, XP009515261, ISSN: 1006-0111
See also references of EP 3524241A4
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
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