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Title:
USE OF INHIBITOR OF PLASMIN INHIBITORY FACTOR FOR PREVENTING OR TREATING PRE-ECLAMPSIA OR ECLAMPSIA
Document Type and Number:
WIPO Patent Application WO/2021/073518
Kind Code:
A1
Abstract:
Provided in the present invention is the use of an inhibitor of a plasmin inhibitory factor for preventing and/or treating pre-eclampsia or eclampsia, or the use thereof in the preparation of a drug for preventing and/or treating pre-eclampsia or eclampsia. Further provided in the present invention is a method for screening a drug candidate for preventing and/or treating pre-eclampsia or eclampsia, the method comprising the step of screening an inhibitor of a plasmin inhibitory factor.

Inventors:
WANG YANLING (CN)
SHAO XUAN (CN)
LI YUXIA (CN)
Application Number:
PCT/CN2020/120781
Publication Date:
April 22, 2021
Filing Date:
October 14, 2020
Export Citation:
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Assignee:
INST ZOOLOGY CAS (CN)
International Classes:
A61K39/395; A61P9/12; A61P15/00
Domestic Patent References:
WO2009108073A12009-09-03
Foreign References:
CN104321076A2015-01-28
CN103513042A2014-01-15
Other References:
LU, HUIFEN ET AL.: "Study on the Effect of Pregnancy Hyperandrogen on Pregnancy Outcome by Mouse Model", THE SECOND JOINT ACADEMIC ANNUAL MEETING OF THE REPRODUCTIVE SCIENCE COMMITTEE OF CHINESE ASSOCIATION FOR PHYSIOLOGICAL SCIENCES AND THE REPRODUCTIVE BIOLOGY BRANCH OF CHINESE ZOOLOGICAL SOCIETY & "THE SECOND ACADEMIC EXCHANGE MEETING OF THE REPRODUC, 25 August 2017 (2017-08-25), XP009527481
XUAN SHAO, YONGQING WANG, YANLEI LIU, XUEJIANG GUO, DONG LI, RAN HUO, WENTONG JIA, GUANGMING CAO, YU-XIA LI, MING LIU, JIAHAO SHA,: "Association of Imbalanced Sex Hormone Production with Excessive Procoagulation Factor SerpinF2 in Preeclampsia.", JOURNAL OF HYPERTENSION, vol. 37, no. 1, 31 January 2019 (2019-01-31), pages 197 - 205, XP009527386, DOI: 10.1097/HJH.0000000000001862
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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