Title:
USE OF LACTOBACILLUS FERMENTUM IN PREPARING PRODUCT FOR PREVENTING AND/OR TREATING THROMBUS
Document Type and Number:
WIPO Patent Application WO/2023/179274
Kind Code:
A1
Abstract:
The present invention belongs to the technical field of microorganisms. Disclosed is use of Lactobacillus fermentum in preparing a product for preventing and/or treating thrombus. Also disclosed is an inhibitory effect of a Lactobacillus fermentum strain CQPC04 (LF-CQPC04) on thrombus formation. Experimental results show that LF-CQPC04 can effectively regulate blood coagulation function, oxidative stress in serum and tissue, and inflammation level. Researches on intestinal flora further show that LF-CQPC04 can regulate the composition of intestinal microorganisms, and may lead to intestinal health by means of increasing beneficial bacteria, thus exerting a good inhibitory effect on thrombus formation.
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Inventors:
MA XIN (CN)
YU YANG (CN)
YU XUEPING (CN)
ZHAO XIN (CN)
YU YANG (CN)
YU XUEPING (CN)
ZHAO XIN (CN)
Application Number:
PCT/CN2023/077307
Publication Date:
September 28, 2023
Filing Date:
February 21, 2023
Export Citation:
Assignee:
THANKCOME BIOLOGICAL SCIENCE AND TECH CO LTD (CN)
International Classes:
C12N1/20; A61K35/747; A61P7/02
Foreign References:
| CN114732834A | 2022-07-12 | |||
| CN109628346A | 2019-04-16 | |||
| CN109481476A | 2019-03-19 | |||
| CN114191490A | 2022-03-18 | |||
| US20110189149A1 | 2011-08-04 | |||
| JP2011132188A | 2011-07-07 |
Other References:
YI RUOKUN, TAN FANG, ZHOU XIANRONG, MU JIANFEI, LI LIN, DU XIPING, YANG ZHENNAI, ZHAO XIN: "Effects of Lactobacillus fermentum CQPC04 on Lipid Reduction in C57BL/6J Mice", FRONTIERS IN MICROBIOLOGY, vol. 11, XP093092070, DOI: 10.3389/fmicb.2020.573586
Attorney, Agent or Firm:
BEIJING SHENGXUN IP AGENT LLC (CN)
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