USE OF MALATE DEHYDROGENASE FOR NADH REGENERATION

Title:

USE OF MALATE DEHYDROGENASE FOR NADH REGENERATION

Document Type and Number:

WIPO Patent Application WO2004022764

Kind Code:

A9

Abstract:

The present invention relates to a process for the preparation of enantiomerically enriched organic compounds. In particular, the present invention relates to an enzymatically operating process, in which, in a coupled enzymatic reaction system, NAD(P)H is consumed by one enzyme for the preparation of the organic compound and the NAD(P)H is simultaneously regenerated by a second enzyme system. A reaction system which operates according to the invention in this manner and an advantageous whole cell catalyst are also proposed.

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Inventors:

NAAMNIEH SHUKRALLAH (DE)
HUMMEL WERNER (DE)
GROEGER HARALD (DE)

Application Number:

PCT/EP2003/008631

Publication Date:

April 14, 2005

Filing Date:

August 05, 2003

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Assignee:

DEGUSSA (DE)
NAAMNIEH SHUKRALLAH (DE)
HUMMEL WERNER (DE)
GROEGER HARALD (DE)

International Classes:

C12N15/09; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/04; C12N9/06; C12P7/40; C12P13/22; C12P19/36; C12P41/00; (IPC1-7): C12P13/04; C12N9/04; C12N15/53; C12P7/04; C12P13/06; C12P41/00; C12P12/22

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