Title:
USE OF MARKER IN DIAGNOSING BREAST CANCER OR PREDICTING BREAST CANCER RISKS
Document Type and Number:
WIPO Patent Application WO/2024/027796
Kind Code:
A1
Abstract:
Disclosed is use of a methylation marker in diagnosing breast cancer or predicting breast cancer risks. Also disclosed is use of a reagent for detecting the methylation level of a marker in preparing a kit or a microarray for diagnosing breast cancer or predicting breast cancer risks in individuals. Further disclosed is a kit or a microarray for diagnosing breast cancer or predicting breast cancer risks in individuals.
Inventors:
SUN JIN (CN)
MA CHENGCHENG (CN)
XU MINJIE (CN)
LIU YIYING (CN)
SU ZHIXI (CN)
LIU RUI (CN)
MA CHENGCHENG (CN)
XU MINJIE (CN)
LIU YIYING (CN)
SU ZHIXI (CN)
LIU RUI (CN)
Application Number:
PCT/CN2023/111009
Publication Date:
February 08, 2024
Filing Date:
August 03, 2023
Export Citation:
Assignee:
SINGLERA GENOMICS CHINA LTD (CN)
International Classes:
C12Q1/68
Foreign References:
| US20170283886A1 | 2017-10-05 | |||
| US20120172238A1 | 2012-07-05 | |||
| US20190256921A1 | 2019-08-22 | |||
| CN101298629A | 2008-11-05 | |||
| CN107034295A | 2017-08-11 |
Other References:
CHEN, LING ET AL.: "Down-regulation of tumor suppressor gene FEZ1/LZTS1 in breast carcinoma involves promoter methylation and associates with metastasis", BREAST CANCER RES TREAT., vol. 116, no. 3, 31 August 2009 (2009-08-31), pages 471 - 478, XP019727895
WANG, XINXIN ET AL.: "Loss of Leucine Zipper Putative Tumor Suppressor 1 (LZTS1) Expression Contributes to Lymph Node Metastasis of Breast Invasive Micropapillary Carcinoma", PATHOL. ONCOL. RES., vol. 21, 27 March 2015 (2015-03-27), pages 1021 - 1026, XP035530316, DOI: 10.1007/s12253-015-9923-x
WANG, XINXIN ET AL.: "Loss of Leucine Zipper Putative Tumor Suppressor 1 (LZTS1) Expression Contributes to Lymph Node Metastasis of Breast Invasive Micropapillary Carcinoma", PATHOL. ONCOL. RES., vol. 21, 27 March 2015 (2015-03-27), pages 1021 - 1026, XP035530316, DOI: 10.1007/s12253-015-9923-x
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
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