Title:
USE OF MATRINE DERIVATIVE IN TREATMENT OF DIABETES MELLITUS
Document Type and Number:
WIPO Patent Application WO/2018/166494
Kind Code:
A1
Abstract:
The present disclosure relates to the use of a compound as shown in formula (I), a stereoisomer thereof, or a pharmaceutically acceptable salt thereof in the preparation of a drug for treating diabetes mellitus, or the use of same in the preparation of a drug for preventing or treating diabetic complications, or the use of same in the preparation of a drug as an insulin sensitizer.
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Inventors:
SONG DANQING (CN)
JIANG JIANDONG (CN)
TANG SHENG (CN)
KONG WEIJIA (CN)
WANG YANXIANG (CN)
WANG CAN (CN)
LI YINGHONG (CN)
LI YUHUAN (CN)
ZHANG JINGPU (CN)
JIANG JIANDONG (CN)
TANG SHENG (CN)
KONG WEIJIA (CN)
WANG YANXIANG (CN)
WANG CAN (CN)
LI YINGHONG (CN)
LI YUHUAN (CN)
ZHANG JINGPU (CN)
Application Number:
PCT/CN2018/079099
Publication Date:
September 20, 2018
Filing Date:
March 15, 2018
Export Citation:
Assignee:
INST MED BIOTECHNOLOGY CAMS (CN)
International Classes:
A61K31/4375; A61P3/10; A61P5/50; A61P13/12; A61P25/28; A61P27/02
Foreign References:
| CN106860449A | 2017-06-20 | |||
| CN106279167A | 2017-01-04 | |||
| CN106905319A | 2017-06-30 |
Other References:
SHENG TANG: "SAR evolution and discovery of benzenesulfonyl matrinanes as a novel class of potential coxsakievirus inhibitors", FUTURE MEDICINAL CHEMISTRY, vol. 8, no. 5, 12 May 2016 (2016-05-12), pages 495 - 508
DU, YAPING ET AL.: "Effect of Oxymatrine on Insulin Resistance in Patients with Type 2 Diabetes Mellitus", WORLD CHINESE JOURNAL OF DIGESTOLOGY, vol. 23, no. 16, 8 June 2015 (2015-06-08), pages 2555 - 2561
JI, YANG ET AL.: "Effect of Matrine on the Content of Blood Glucose and Liver Glycogen of Mice with Alloxan-Induced Diabetes", ACTA MEDICA SINICA, vol. 17, no. 07, 15 July 2002 (2002-07-15), pages 436 - 437
DU, YAPING ET AL.: "Effect of Oxymatrine on Insulin Resistance in Patients with Type 2 Diabetes Mellitus", WORLD CHINESE JOURNAL OF DIGESTOLOGY, vol. 23, no. 16, 8 June 2015 (2015-06-08), pages 2555 - 2561
JI, YANG ET AL.: "Effect of Matrine on the Content of Blood Glucose and Liver Glycogen of Mice with Alloxan-Induced Diabetes", ACTA MEDICA SINICA, vol. 17, no. 07, 15 July 2002 (2002-07-15), pages 436 - 437
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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