USE OF PLANT-DERIVED EXOSOMES FOR INDUCING DIFFERENTIATION OF STEM CELL SOURCES INTO CARTILAGE AND BONE CELLS

WIPO Patent Application WO/2022/146374

A3

The present invention relates to a product comprising plant-derived nanovesicles which induce differentiation of the stem cell sources into cartilage and bone cells. The objective of the invention is to improve the rate of differentiation into cartilage and bone cells, enhance strength of the obtained tissue and to provide a non-toxic application with lower cost by means of giving plant exosomes in addition to the differentiation media to the adipose-derived stem cells.

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SAHIN FIKRETTIN (TR)
KOCAK POLEN (TR)
YILDIRIM MERVE (TR)

PCT/TR2021/051534

October 06, 2022

December 27, 2021

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UNIV YEDITEPE (TR)

A61K35/28; A61K9/08; A61K35/32

WO2019027387A2

2019-02-07

EP3235500A2

2017-10-25

WANG JIAN-MEI, GU YAN, PAN CAI-JUN, YIN LI-RONG: "Isolation, culture and identification of human adipose-derived stem cells", EXPERIMENTAL AND THERAPEUTIC MEDICINE, SPANDIDOS PUBLICATIONS, GR, vol. 13, no. 3, 1 March 2017 (2017-03-01), GR , pages 1039 - 1043, XP055976716, ISSN: 1792-0981, DOI: 10.3892/etm.2017.4069

ANKARA PATENT BUREAU (TR)

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