Title:
USE OF REPRESENTATIONS OF DNA FOR GENETIC ANALYSIS
Document Type and Number:
WIPO Patent Application WO2001083822
Kind Code:
A3
Abstract:
It is an object of the present invention to provide a solution to problems associated with the use of microarray technology for the analysis DNA. The present invention provides compositions and methods for the use of simple and compound representations of DNA in microarray technology. The present invention is also directed to methods for the production of High Complexity Representations (HCRs) of the DNA from cells.
Inventors:
WIGLER MICHAEL
LUCITO ROBERT
LUCITO ROBERT
Application Number:
PCT/US2001/013949
Publication Date:
March 20, 2003
Filing Date:
May 01, 2001
Export Citation:
Assignee:
COLD SPRING HARBOR LAB (US)
International Classes:
C12Q1/68; (IPC1-7): C12Q1/68
Domestic Patent References:
| WO1998028438A1 | 1998-07-02 | |||
| WO1999039001A2 | 1999-08-05 | |||
| WO1999005321A1 | 1999-02-04 | |||
| WO1999023256A1 | 1999-05-14 | |||
| WO1994011383A1 | 1994-05-26 |
Foreign References:
| US6013431A | 2000-01-11 | |||
| EP0408918A1 | 1991-01-23 | |||
| US5710000A | 1998-01-20 |
Other References:
PASTINEN T ET AL: "MINISEQUENCING: A SPECIFIC TOOL FOR DNA ANALYSIS AND DIAGNOSTICS ONOLIGONUCLEOTIDE ARRAYS", PCR METHODS AND APPLICATIONS, COLD SPRING HARBOR, NY, US, 1997, pages 606 - 614, XP002930983, ISSN: 1054-9803
OROSKAR ET AL: "DETECTION OF IMMOBILIZED AMPLICONS BY ELISA-LIKE TECHNIQUES", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY. WINSTON, US, XP002074418, ISSN: 0009-9147
LUCITO ROBERT ET AL: "Genetic analysis using genomic representations.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 95, no. 8, 14 April 1998 (1998-04-14), April 14, 1998, pages 4487 - 4492, XP002222194, ISSN: 0027-8424
LUCITO ROBERT ET AL: "Detecting gene copy number fluctuations in tumor cells by microarray analysis of genomic representations.", GENOME RESEARCH, vol. 10, no. 11, November 2000 (2000-11-01), pages 1726 - 1736, XP002222195, ISSN: 1088-9051
OROSKAR ET AL: "DETECTION OF IMMOBILIZED AMPLICONS BY ELISA-LIKE TECHNIQUES", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY. WINSTON, US, XP002074418, ISSN: 0009-9147
LUCITO ROBERT ET AL: "Genetic analysis using genomic representations.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 95, no. 8, 14 April 1998 (1998-04-14), April 14, 1998, pages 4487 - 4492, XP002222194, ISSN: 0027-8424
LUCITO ROBERT ET AL: "Detecting gene copy number fluctuations in tumor cells by microarray analysis of genomic representations.", GENOME RESEARCH, vol. 10, no. 11, November 2000 (2000-11-01), pages 1726 - 1736, XP002222195, ISSN: 1088-9051
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