Title:
USNIC ACID DERIVATIVE HAVING ABILITY TO INHIBIT TSLP SECRETION, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/076100
Kind Code:
A1
Abstract:
The present invention relates to a novel Usnic acid derivative exhibiting an inhibitory effect on TSLP secretion or pharmaceutically acceptable salts thereof, and a use thereof.
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Inventors:
HEO CHAN YEONG (KR)
KANG SO MIN (KR)
JEON DASOM (KR)
KANG SO MIN (KR)
JEON DASOM (KR)
Application Number:
PCT/KR2019/013305
Publication Date:
April 16, 2020
Filing Date:
October 10, 2019
Export Citation:
Assignee:
SEOUL NAT UNIV HOSPITAL (KR)
International Classes:
C07D307/91; A61K8/49; A61K31/343; A61P37/08; A61Q19/00
Domestic Patent References:
| WO2012131347A1 | 2012-10-04 | |||
| WO2017134594A1 | 2017-08-10 |
Foreign References:
| CN102526019A | 2012-07-04 | |||
| KR20180120342A | 2018-11-06 | |||
| KR20190124901A | 2019-11-06 |
Other References:
INDRA, A. K.: "Epidermal TSLP: a trigger factor for pathogenesis of atopic dermatitis", EXPERT REVIEW OF PROTEOMICS, vol. 10, no. 4, 2013, pages 309 - 311, XP009527205, DOI: 10.1586/14789450.2013.814881
SHTRO, A. A.: "Novel derivatives of usnic acid effectively inhibiting reproduction of influenza A virus", BIOORGANIC & MEDICINAL CHEMISTRY, 2014, pages 6826 - 6836, XP029102541, DOI: 10.1016/j.bmc.2014.10.033
S. KANG; C. HEO; D. JEON: "075 Effect of novel usnic acid derivative on atopic dermatitis", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 139, no. 5, May 2019 (2019-05-01), pages S13, XP009527096, DOI: 10.1016/j.jid.2019.03.151
STEVEN F. ZIEGLER ET AL., J ALLERGY CLIN IMMUNOL, vol. 130, 2012, pages 845 - 52
JUAN ET AL., JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2012
See also references of EP 3858822A4
SHTRO, A. A.: "Novel derivatives of usnic acid effectively inhibiting reproduction of influenza A virus", BIOORGANIC & MEDICINAL CHEMISTRY, 2014, pages 6826 - 6836, XP029102541, DOI: 10.1016/j.bmc.2014.10.033
S. KANG; C. HEO; D. JEON: "075 Effect of novel usnic acid derivative on atopic dermatitis", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 139, no. 5, May 2019 (2019-05-01), pages S13, XP009527096, DOI: 10.1016/j.jid.2019.03.151
STEVEN F. ZIEGLER ET AL., J ALLERGY CLIN IMMUNOL, vol. 130, 2012, pages 845 - 52
JUAN ET AL., JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2012
See also references of EP 3858822A4
Attorney, Agent or Firm:
DARAE LAW & IP, LLC (KR)
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