VACCINE AGAINST THE INFLUENZA VIRUS AND METHOD FOR PRODUCING SAID VIRUS VACCINE

WIPO Patent Application WO/2002/011758

A1

The inventive vaccine against an influenza virus is embodied in the form of a composition of derivatives of heterochain polyamines with vaccinal antigens of the influenza virus. Said composition can be produced by means of interacting the vaccinal antigens of the influenza virus with derivatives of the heterochain polyamines with the aid of an aride method in the form of a conjugate of general formula (1): where: R - vaccine antigens of the influenza virus; n the number of elementary linkages: q the number of alkyl linkages; z the number of oxidised linkages. The vaccine can also be produced in the form of a complex composition of vaccinal antigens of the influenza virus with derivatives of the heterochain polyamines which are obtained by a complex-forming reaction ensuring strong electrostatic links.

PETROV REM VIKTOROVICH (RU)
KHAITOV RAKHIM MUSAEVICH (RU)
NEKRASOV ARKADY VASILIEVICH (RU)
PUCHKOVA NATALYA GRIGORIEVNA (RU)
IVANOVA ALBERTA SERGEEVNA (RU)

PCT/RU2001/000229

February 14, 2002

June 13, 2001

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PETROV REM VIKTOROVICH (RU)
KHAITOV RAKHIM MUSAEVICH (RU)
NEKRASOV ARKADY VASILIEVICH (RU)
PUCHKOVA NATALYA GRIGORIEVNA (RU)
IVANOVA ALBERTA SERGEEVNA (RU)

A61K39/145; A61K39/385; A61K47/48; A61P31/12; A61P31/16; (IPC1-7): A61K39/145; A61K39/385; A61K39/39; A61K47/32; A61K47/48; A61P31/12

SU1580617A1	1997-02-10
RU2112542C1	1998-06-10
RU2153354C1	2000-07-27
RU2073031C1	1997-02-10

Ivanova, Tatyana Pavlovna (Kashirskoe shosse 24-2 Moscow, 8, RU)

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