Title:
VEGF-B AND PDGF MODULATION OF STEM CELLS
Document Type and Number:
WIPO Patent Application WO2004070018
Kind Code:
A3
Abstract:
The present invention provides materials and methods for VEGF-B AND PDGF therapy, especially therapy directed at stem cell recruitment, proliferation, and/or differentiation.
Inventors:
ALITALO KARI (FI)
ERIKSSON ULF (SE)
CARMELIET PETER (BE)
LI XURI (SE)
COLLEN DESIRE (BE)
YLA-HERTTUALA SEPPO (FI)
SALVEN PETRI (FI)
RAJANTIE IIRO (FI)
ERIKSSON ULF (SE)
CARMELIET PETER (BE)
LI XURI (SE)
COLLEN DESIRE (BE)
YLA-HERTTUALA SEPPO (FI)
SALVEN PETRI (FI)
RAJANTIE IIRO (FI)
Application Number:
PCT/US2004/003316
Publication Date:
February 03, 2005
Filing Date:
February 04, 2004
Export Citation:
Assignee:
LUDWIG INST CANCER RES (US)
LICENTIA LTD (FI)
FLANDERS INTERUNIVERSITY INST (BE)
ALITALO KARI (FI)
ERIKSSON ULF (SE)
CARMELIET PETER (BE)
LI XURI (SE)
COLLEN DESIRE (BE)
YLA-HERTTUALA SEPPO (FI)
SALVEN PETRI (FI)
RAJANTIE IIRO (FI)
LICENTIA LTD (FI)
FLANDERS INTERUNIVERSITY INST (BE)
ALITALO KARI (FI)
ERIKSSON ULF (SE)
CARMELIET PETER (BE)
LI XURI (SE)
COLLEN DESIRE (BE)
YLA-HERTTUALA SEPPO (FI)
SALVEN PETRI (FI)
RAJANTIE IIRO (FI)
International Classes:
A61K35/545; A61K38/18; A61K38/19; A61K48/00; A61P7/00; A61P9/10; C12N5/07; C12N5/0789; C12N15/861; (IPC1-7): A61K38/18; A61K38/19; A61P9/10; A61P7/00
Domestic Patent References:
| WO2003000009A2 | 2003-01-03 | |||
| WO2002095038A2 | 2002-11-28 | |||
| WO1998007832A1 | 1998-02-26 |
Foreign References:
| US20020022270A1 | 2002-02-21 | |||
| US5753506A | 1998-05-19 |
Other References:
HAMADA K ET AL: "VEGF-C SIGNALING PATHWAYS THROUGH VEGFR-2 AND VEGFR-3 IN VASCULOANGIOGENESIS AND HEMATOPOIESIS", BLOOD, W.B.SAUNDERS COMPAGNY, ORLANDO, FL, US, vol. 96, no. 12, 2000, pages 3793 - 3800, XP002952145, ISSN: 0006-4971
HUANG X-L ET AL: "IN VITRO EFFECTS OF ANGIOPOIETINS AND VEGF ON HEMATOPOIETIC AND ENDOTHELIAL CELLS", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 264, no. 1, 1999, pages 133 - 138, XP002908384, ISSN: 0006-291X
HUANG X-L ET AL: "IN VITRO EFFECTS OF ANGIOPOIETINS AND VEGF ON HEMATOPOIETIC AND ENDOTHELIAL CELLS", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 264, no. 1, 1999, pages 133 - 138, XP002908384, ISSN: 0006-291X
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