Title:
VIOLOGEN-FUNCTIONALIZED PORPHYRINS FOR REDUCING BIOFOULING ON SURFACES
Document Type and Number:
WIPO Patent Application WO/2017/031173
Kind Code:
A8
Abstract:
Disclosed herein are novel amine-functionalized porphyrin compounds, as wells as pharmaceutically acceptable salts or esters thereof. The disclosed compounds can be used to impart antioxidant, antiinflammatory, anti-microbial, and/or cell-adhesion specificity to a surface or material in need thereof, such as a surface of an indwelling medical implant, or a marine surface. The porphyrine compounds are characterized by having the following group attached to the porphyrine core through a carboxylate ester group. A is independently an optionally substituted N-heterocyclic aromatic ring; x is independently an integer from 0 to 6; R2 is independently lower aminoalkyl or lower aminoaryl.
Inventors:
CUI XINYAN (US)
SNYDER NOAH (US)
CATT KASEY (US)
ELES JAMES (US)
SNYDER NOAH (US)
CATT KASEY (US)
ELES JAMES (US)
Application Number:
PCT/US2016/047290
Publication Date:
April 13, 2017
Filing Date:
August 17, 2016
Export Citation:
Assignee:
UNIV OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US)
International Classes:
C07F13/00; A61L27/28; A61L29/08; A61L31/08; C07D487/22; C07F3/02; C07F15/02
Attorney, Agent or Firm:
SCOTT, Gregory, K. (US)
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