Title:
WATER-SOLUBLE PHENYLPYRIDAZINE DERIVATIVE AND MEDICINE CONTAINING THE SAME
Document Type and Number:
WIPO Patent Application WO/2004/083188
Kind Code:
A1
Abstract:
A phenylpyridazine derivative represented by the general formula (1): (1) (wherein R1, R2, R3, X, Y, Z, and n are the same as defined in the description) or a salt thereof; and a medicine containing the derivative or salt. The phenylpyridazine derivative has excellent interleukin-1β production inhibitory activity and has high water solubility and high oral absorbability.
Inventors:
KYOTANI YOSHINORI (JP)
KOSHI TOMOYUKI (JP)
SHIGYO HIROMICHI (JP)
YOSHIZAKI HIDEO (JP)
KITAMURA TAKAHIRO (JP)
TAKEMURA SHUNJI (JP)
YASUOKA KYOKO (JP)
TOTSUKA JUNKO (JP)
SATO SEIICHI (JP)
KOSHI TOMOYUKI (JP)
SHIGYO HIROMICHI (JP)
YOSHIZAKI HIDEO (JP)
KITAMURA TAKAHIRO (JP)
TAKEMURA SHUNJI (JP)
YASUOKA KYOKO (JP)
TOTSUKA JUNKO (JP)
SATO SEIICHI (JP)
Application Number:
PCT/JP2004/003487
Publication Date:
September 30, 2004
Filing Date:
March 16, 2004
Export Citation:
Assignee:
KOWA CO (JP)
KYOTANI YOSHINORI (JP)
KOSHI TOMOYUKI (JP)
SHIGYO HIROMICHI (JP)
YOSHIZAKI HIDEO (JP)
KITAMURA TAKAHIRO (JP)
TAKEMURA SHUNJI (JP)
YASUOKA KYOKO (JP)
TOTSUKA JUNKO (JP)
SATO SEIICHI (JP)
KYOTANI YOSHINORI (JP)
KOSHI TOMOYUKI (JP)
SHIGYO HIROMICHI (JP)
YOSHIZAKI HIDEO (JP)
KITAMURA TAKAHIRO (JP)
TAKEMURA SHUNJI (JP)
YASUOKA KYOKO (JP)
TOTSUKA JUNKO (JP)
SATO SEIICHI (JP)
International Classes:
A61K31/50; A61K31/501; A61P9/10; A61P19/10; A61P29/00; A61P31/04; A61P37/06; A61P43/00; C07D237/14; (IPC1-7): C07D237/14; A61K31/50; A61K31/501; A61P37/06; A61P29/00; A61P9/10; A61P31/04; A61P19/10; A61P43/00
Domestic Patent References:
| WO2003027077A1 | 2003-04-03 | |||
| WO1999044995A1 | 1999-09-10 |
Attorney, Agent or Firm:
The, Patent Corporate Body Aruga Patent Office (3-6 Nihonmashiningyocho 1-chom, Chuo-ku Tokyo 13, JP)
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