Title:
WATER-SOLUBLE STEROL DERIVATIVES CAPABLE OF LOWERING CHOLESTEROL LEVELS AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2010/114339
Kind Code:
A2
Abstract:
The present invention relates to water-soluble sterol derivatives capable of lowering cholesterol levels and a preparation method thereof. The preparation method of water-soluble sterol derivatives according to the present invention comprises: in the presence of a basic catalyst in a non-polar organic solvent, mixing a phytosterol intermediate and polyethylene glycol (PEG) having a weight average molecular weight of 200 to 1,000 at a molar ratio ranging from 1:2 to 1:6, followed by adding a coupling agent to allow a coupling reaction to occur. This method of the present invention using a PEG oligomer as a carrier and controlling the molecular structure of a product can therefore provide water-soluble sterol derivatives capable of lowering cholesterol levels, in which the derivatives are soluble in water at a high concentration of at least about 3.0% by weight with respect to sterol and safer to use for the body and thus useful as a water-soluble food or as a material of medicine.
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Inventors:
CHUNG DAE-WON (KR)
NOH SEUNG-KWON (KR)
NOH SEUNG-KWON (KR)
Application Number:
PCT/KR2010/002049
Publication Date:
October 07, 2010
Filing Date:
April 02, 2010
Export Citation:
Assignee:
CHUNG DAE-WON (KR)
NOH SEUNG-KWON (KR)
NOH SEUNG-KWON (KR)
International Classes:
C07J75/00; C07J9/00
Domestic Patent References:
| WO2010114320A2 | 2010-10-07 |
Foreign References:
| KR20020029718A | 2002-04-19 | |||
| KR20000012167A | 2000-03-06 | |||
| KR20000012170A | 2000-03-06 | |||
| JPH03145420A | 1991-06-20 |
Attorney, Agent or Firm:
C&S LOGOS PATENT AND LAW OFFICE (KR)
특허법인 씨엔에스·로고스 (KR)
특허법인 씨엔에스·로고스 (KR)
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