WATER-SOLUBLE TETRAZOLIUM SALT COMPOUNDS

Title:

WATER-SOLUBLE TETRAZOLIUM SALT COMPOUNDS

Document Type and Number:

WIPO Patent Application WO/1997/038985

Kind Code:

A1

Abstract:

Tetrazolium salt compounds represented by general formula (1): wherein R1 and R2 each independently represent a hydrogen atom, a nitro group, a cyano group, a carboxyl group, or a halogen atom, preferably a nitro group; R3 represents an alkyl or alkoxyl group, preferably a methyl or methoxy group; and M represents an alkali metal or an ammonium. The compounds are useful for the quantitative determination of dehydrogenases and have high water solubility and storage stability in an aqueous solution form.

Inventors:

ISHIYAMA MUNETAKA (JP)
MIYAZONO YOKO (JP)
SHIGA MASANOBU (JP)
SASAMOTO KAZUMI (JP)

Application Number:

PCT/JP1997/001324

Publication Date:

October 23, 1997

Filing Date:

April 17, 1997

Export Citation:

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Assignee:

DOJINDO LAB CO LTD (JP)
ISHIYAMA MUNETAKA (JP)
MIYAZONO YOKO (JP)
SHIGA MASANOBU (JP)
SASAMOTO KAZUMI (JP)

International Classes:

C07C309/59; C07D257/04; C07D417/14; C12Q1/32; G01N33/58; (IPC1-7): C07D257/04; C12Q1/32; C07C309/46

Foreign References:

JPH0770092A	1995-03-14
JPS5661366A	1981-05-26
JPS5661367A	1981-05-26

Other References:

CHEMICAL & PHARMACEUTICAL BULLETIN, Vol. 41, No. 6, (1993), ISHIYAMA M. et al., "A New Tetrazorium Salt that Produces a Highly Water-Soluble Formazan Dye", p. 1118-1122.
See also references of EP 0908453A4

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