Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
WICKEROL AND PROCESS FOR PRODUCTION THEREOF
Document Type and Number:
WIPO Patent Application WO/2009/116604
Kind Code:
A1
Abstract:
Disclosed is wickerol. Also disclosed is a process for producing wickerol, which comprises the steps of: culturing Trichoderma atroviride strain FKI-3737 (FERM ABP-11099) (which is a filamentous bacterium) in a culture medium to accumulate wickerol in a culture; and isolating and purifying wickerol from the culture. Further disclosed is an effective inhibitor of the proliferation of an influenza virus, which comprises wickerol as an active ingredient. Still further disclosed is an effective anti-influenza agent which comprises wickerol as an active ingredient.

Inventors:
OMURA SATOSHI (JP)
SHIOMI KAZURO (JP)
MASUMA ROKURO (JP)
UI HIDEAKI (JP)
NAGAI TAKAYUKI (JP)
YAMADA HIROKI (JP)
Application Number:
PCT/JP2009/055367
Publication Date:
September 24, 2009
Filing Date:
March 12, 2009
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KITASATO INST (JP)
OMURA SATOSHI (JP)
SHIOMI KAZURO (JP)
MASUMA ROKURO (JP)
UI HIDEAKI (JP)
NAGAI TAKAYUKI (JP)
YAMADA HIROKI (JP)
International Classes:
C12P15/00; A61K31/045; A61P31/16; C07C35/44; C12N1/14; C12P7/02; C12R1/885
Foreign References:
JPH0494693A1992-03-26
JPS4920389A1974-02-22
Other References:
"Abstracts of 128th Annual Meeting of Pharmaceutical Society of Japan 2", 5 March 2008, article HIDEAKI UI ET AL.: "Shijokin no Seisan suru Shinki Ko-Influenza Virus Busshitsu no Tanri, Kozo Oyobi Kassei", pages: 126, XP008143595
FUKAMI A. ET AL.: "A new anti-influenza virus antibiotic, 10-norparvulenone from Microsphaeropsis sp. FO-5050", J. ANTIBIOT., vol. 53, no. 10, October 2000 (2000-10-01), pages 1215 - 1218, XP008141417
Attorney, Agent or Firm:
KOBAYASHI, Kazunori (25-1 Kitaotsuka 2-chome, Toshima-k, Tokyo ., JP)
Download PDF: