Title:
X-RAY DEVELOPING COMPOUND AND PREPARATION METHOD THEREFOR, AND X-RAY DEVELOPING MICROSPHERE AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2024/060825
Kind Code:
A1
Abstract:
The present invention relates to an X-ray developing compound and a preparation method therefor, and an X-ray developing microsphere and a preparation method therefor, and belongs to the technical field of embolization visualization under X-rays. The X-ray developing compound has a structural formula shown as follows: (I), wherein n is an integer from 1 to 5. According to the developing compound, an iodo aryl group and an epoxy group are connected by means of an ether bond to form the X-ray developing compound. The epoxy group in the developing compound is easy to subject to a one-step reaction with a hydroxyl group in a polyvinyl alcohol microsphere, such that the polyvinyl alcohol microsphere has a developing function, and the prepared developing microsphere has good hydrophilicity.
Inventors:
SUN HONGTAO (CN)
LI XIN (CN)
SUN PENG (CN)
LI XIN (CN)
SUN PENG (CN)
Application Number:
PCT/CN2023/109266
Publication Date:
March 28, 2024
Filing Date:
July 26, 2023
Export Citation:
Assignee:
CARDIOLINK SCIENCE SHENZHEN MEDICAL TECH DEVELOPMENT CO LTD (CN)
International Classes:
A61K49/04; C07D303/22; C08G65/26
Foreign References:
| CN114259599A | 2022-04-01 | |||
| CN114805644A | 2022-07-29 | |||
| CN115590984A | 2023-01-13 | |||
| CN102781974A | 2012-11-14 |
Other References:
REDDY, M. N. ET AL.: "Dual catalysis by Cu(I): facile single step click and intramolecular C–O bond formation leading to triazole tethered dihydrobenzodioxines/benzoxazines/ benzoxathiines/benzodioxepines", ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 11, no. 42, 14 November 2013 (2013-11-14), XP055919815, ISSN: 1477-0520, DOI: 10.1039/c3ob41332b
Attorney, Agent or Firm:
CHOFN INTELLECTUAL PROPERTY (CN)
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