Title:
XYLANASE MUTANT AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/054244
Kind Code:
A1
Abstract:
A xylanase mutant and application thereof. The amino acid sequence of the xylanase mutant is as shown in SEQ ID No：1; and the xylanase mutant is obtained by coding amino acids in fungal Neocallimastigomycota xylanase amino acid sequence SEQ ID No：3 to cause the following changes N207S，G208S，A210S. The mutant can well act in gastrointestinal environment of livestock and poultry and has a relatively ideal heat resistant property; therefore, the mutant is particular suitable for being used as a feed additive.
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Inventors:
HUANG ZUNXI (CN)
MIAO HUABIAO (CN)
HAN NANYU (CN)
MIAO HUABIAO (CN)
HAN NANYU (CN)
Application Number:
PCT/CN2017/101394
Publication Date:
March 29, 2018
Filing Date:
September 12, 2017
Export Citation:
Assignee:
UNIV YUNNAN (CN)
International Classes:
C12N9/24; A23K20/00; A23K20/189; C12N1/00; C12N1/19; C12N9/00; C12N15/00; C12N15/56; C12N15/81
Foreign References:
| CN106282141A | 2017-01-04 | |||
| CN104109660A | 2014-10-22 | |||
| CN102757947A | 2012-10-31 | |||
| CN101392266A | 2009-03-25 |
Other References:
HAN, N.Y. ET AL.: "Improving the thermostability of a fungal GH11 xylanase via site-directed mutagenesis guided by sequence and structural analysis", BIOTECHNOL BIOFUELS., vol. 10, no. 133, 23 May 2017 (2017-05-23), pages 1 - 12, XP055603187, DOI: 10.1186/s13068-017-0824-y
DATABASE Nucleotide 12 March 2015 (2015-03-12), "PREDOCTED: Homo sapiens receptor-interacting serine-threonine kinase 2 (RIPK2), transcript variant X2, mRNA", XP055603193, retrieved from NCBI Database accession no. XM_011517357. 1
DATABASE Nucleotide 12 March 2015 (2015-03-12), "PREDOCTED: Homo sapiens receptor-interacting serine-threonine kinase 2 (RIPK2), transcript variant XI, mRNA", XP055603194, retrieved from NCBI Database accession no. XM_005251092. 2
DATABASE Nucleotide 12 March 2015 (2015-03-12), "PREDOCTED: Homo sapiens receptor-interacting serine-threonine kinase 2 (RIPK2), transcript variant X2, mRNA", XP055603193, retrieved from NCBI Database accession no. XM_011517357. 1
DATABASE Nucleotide 12 March 2015 (2015-03-12), "PREDOCTED: Homo sapiens receptor-interacting serine-threonine kinase 2 (RIPK2), transcript variant XI, mRNA", XP055603194, retrieved from NCBI Database accession no. XM_005251092. 2
Attorney, Agent or Firm:
BEIJING ZHCC INTELLECTUAL PROPERTY CO., LTD. (CN)
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