Title:
YEAST SINGLE NUCLEOTIDE POLYMORPHISMS FOR INDUSTRIALLY RELEVANT PHENOTYPES
Document Type and Number:
WIPO Patent Application WO/2023/280976
Kind Code:
A3
Abstract:
The present invention relates to the field of yeast fermentations. More particularly, the invention relates to mutant alleles useful to engineer industrially relevant traits in yeast.
Inventors:
VERSTREPEN KEVIN (BE)
HO PING-WEI (BE)
JAROSZ DAN (US)
HO PING-WEI (BE)
JAROSZ DAN (US)
Application Number:
PCT/EP2022/068897
Publication Date:
February 09, 2023
Filing Date:
July 07, 2022
Export Citation:
Assignee:
VIB VZW (BE)
KATHOLIEKE UNIV LEUVEN K U LEUVEN R&D (BE)
UNIV LELAND STANFORD JUNIOR (US)
KATHOLIEKE UNIV LEUVEN K U LEUVEN R&D (BE)
UNIV LELAND STANFORD JUNIOR (US)
International Classes:
C12N1/16; A61K36/06; C12N15/80; C12P7/16; C12P7/54
Foreign References:
| US20110201090A1 | 2011-08-18 |
Other References:
PAPAPETRIDIS ET AL: "Improving ethanol yield in acetate-reducing Saccharomyces cerevisiaecofactor engineering of 6-phosphogluconate dehydrogenase and deletion of ALD6", MICROBIAL CELL FACTORIES,, vol. 15, 26 April 2016 (2016-04-26), pages 1 - 16, XP002768961
OFFEI BENJAMIN ET AL: "Unique genetic basis of the distinct antibiotic potency of high acetic acid production in the probiotic yeast Saccharomyces cerevisiae var. boulardii", GENOME RESEARCH, vol. 29, no. 9, 1 September 2019 (2019-09-01), US, pages 1478 - 1494, XP055974568, ISSN: 1088-9051, Retrieved from the Internet DOI: 10.1101/gr.243147.118
WESS JOHANNES ET AL: "Improving isobutanol production with the yeast Saccharomyces cerevisiae by successively blocking competing metabolic pathways as well as ethanol and glycerol formation", BIOTECHNOLOGY FOR BIOFUELS, vol. 12, no. 1, 1 December 2019 (2019-12-01), pages 173, XP055974620, Retrieved from the Internet DOI: 10.1186/s13068-019-1486-8
HO PING-WEI ET AL: "Massive QTL analysis identifies pleiotropic genetic determinants for stress resistance, aroma formation, and ethanol, glycerol and isobutanol production in Saccharomyces cerevisiae", BIOTECHNOLOGY FOR BIOFUELS, vol. 14, no. 1, 2 November 2021 (2021-11-02), XP055974579, Retrieved from the Internet DOI: 10.1186/s13068-021-02059-w
OFFEI BENJAMIN ET AL: "Unique genetic basis of the distinct antibiotic potency of high acetic acid production in the probiotic yeast Saccharomyces cerevisiae var. boulardii", GENOME RESEARCH, vol. 29, no. 9, 1 September 2019 (2019-09-01), US, pages 1478 - 1494, XP055974568, ISSN: 1088-9051, Retrieved from the Internet
WESS JOHANNES ET AL: "Improving isobutanol production with the yeast Saccharomyces cerevisiae by successively blocking competing metabolic pathways as well as ethanol and glycerol formation", BIOTECHNOLOGY FOR BIOFUELS, vol. 12, no. 1, 1 December 2019 (2019-12-01), pages 173, XP055974620, Retrieved from the Internet
HO PING-WEI ET AL: "Massive QTL analysis identifies pleiotropic genetic determinants for stress resistance, aroma formation, and ethanol, glycerol and isobutanol production in Saccharomyces cerevisiae", BIOTECHNOLOGY FOR BIOFUELS, vol. 14, no. 1, 2 November 2021 (2021-11-02), XP055974579, Retrieved from the Internet
Attorney, Agent or Firm:
DEMOLDER, Jan (BE)
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