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WO/2006/036964A2 |
A barrier layer and corresponding method of making provide anti-inflammatory, non-inflammatory, and anti-adhesion functionality for a medical device implantable in a patient. The barrier layer can be combined with a medical device struct...
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WO/2006/036984A2 |
A stand-alone film is derived at least in part from fatty acids. The stand-alone film can have anti-adhesive, anti-inflammatory, non-inflammatory, and wound healing properties, and can additionally include one or more therapeutic agents ...
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WO/2006/020659A2 |
The present invention is directed to a method for coating a surface of a medical device with a coating composition. The method involves chilling the surface to be coated to below the freezing point of at least one solvent contained in th...
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WO/2006/017169A2 |
[0001] All or a portion of a surface of an implantable sensor is covered with a biocompatible coating formed at least partially of a biomaterial matrix having properties that promote a substantially even growth of tissue cells over the s...
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WO/2006/009179A1 |
A direct hemoperfusion adsorber that comprises a water insoluble support having a relatively easily procurable particle diameter distribution without the need to install special granulation equipment and coating equipment, and that is pa...
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WO/2006/004686A2 |
The invention relates to a bioceramic coated apparatus and method of forming the same. The apparatus may be a medical implant such as, for example, an orthopedic implant or a dental implant. The bioceramic coating is designed to increase...
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WO/2005/123149A1 |
The invention relates to a lock solution for medical devices comprising carbohydrates and/or glucose degradation products as antimicrobial agent(s).
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WO/2005/118020A1 |
Coatings comprising protein resistant components and therapeutic components on medical devices are disclosed. The coatings act to down-regulate complement activation. Medical devices can be coated with these coatings to prevent side effe...
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WO/2005/118018A1 |
A medical device comprising a coating thereon comprising a biocompatible polymer and heparin is provided herein. Heparin is coupled with the biocompatible polymer via a spacer having a grouping that renders a binding site of the heparin ...
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WO/2005/115490A2 |
Polymeric coatings that include coupled biomolecules are formed on the surface of articles, such as medical devices. A coated layer that includes a synthetic polymer including a reactive group is formed on a surface and then a biomolecul...
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WO/2005/113620A1 |
A biocompatible material which little causes interaction with biocomponents such as proteins or blood cells and is excellent in biocompatibility, that is, a biocompatible material consisting of a polymer obtained by polymerizing a monome...
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WO/2005/097223A1 |
The invention provides methods and compositions for providing biocompatible surfaces to medical articles. In particular the invention provides biocompatible coatings with heparin activity. In some aspects, the biocompatible coatings of t...
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WO/2005/097222A1 |
The invention provides methods and compositions for providing biocompatible surfaces to medical articles. In particular the invention provides biocompatible coatings with heparin activity that are able to release a bioactive agent, where...
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WO/2005/079883A1 |
A method and a coating on a tampon applicator. The coating includes a crosslinked hydrogel that includes a copolymer including water soluble base polymers having graft polymerized thereto organic moieties that react with water to form a ...
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WO/2005/072786A1 |
A multi-step method of manufacturing a medical device containing therapeutic agents that results in a lower maximum error in the amount of therapeutic agents actually disposed thereon and that allows for differential drug release kinetic...
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WO/2005/053765A1 |
The invention relates to a metallic substrate characterised in that it is coated with a coating composition comprising at least one type of polysaccharide compound, at least one type of collagen and at least one glycerol and glycol polye...
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WO/2005/051449A1 |
Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.
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WO/2005/032611A2 |
The invention relates to medical products comprising at least one biocompatible biostable polysulfone coating. Said polysulfone coating makes it possible, via the admixture of an adequate quantity of at least one hydrophilic polymer, to ...
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WO/2005/030282A1 |
The present invention relates to devices carrying on the surface polymeric micelles and a process for the preparation thereof. It further relates to the use of polymeric micelles as a surface coating for rendering a surface anti-fouling ...
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WO/2005/030094A1 |
This invention relates to stents having tacrolimus and/or everolimus containing medicated multi-layer hybrid polymer coatings, useful for the treatment of stenosed vasculature or other body passages.
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WO/2005/027852A2 |
The present invention relates to improved methods for reducing pain and organ dysfunction using bioadhesive, bioresorbable, anti-adhesion compositions made of intermacromolecular complexes of carboxyl-containing polysaccharides, polyethe...
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WO/2005/023292A1 |
Restenosis in a subject can be treated by administering to a tissue, e.g., a blood vessel, of the subject an agent that increases SERCA activity. For example, a stent that is coated with the agent can be introduced into a blood vessel.
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WO/2005/021139A1 |
A unit element forming a membrane comprising a semi-permeable material able to separate in two compartments a filtration device for extracorporeal treatment of fluid. The material is negatively charged and the element has a first interna...
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WO/2005/004945A2 |
A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition which can result in reduction of the rate of release of an active agent fro...
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WO/2005/002640A1 |
The invention relates to a modular coating system for bio-materials, used in medical products that are in direct contact with the blood. Said coating system comprises a synthetic blood coagulation inhibitor layer, which is bonded to the ...
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WO/2004/108146A1 |
It is intended to provide a means whereby cells having a wound-healing effect are efficiently concentrated within a short period of time and thus utilized as a material promoting wound healing. Namely, a material promoting wound healing ...
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WO/2004/096307A1 |
The invention provides a self-sealing arteriovenous graft including a tube having a polymeric inner layer defining a lumen through which blood may flow and an outer textile layer. The outer textile layer is concentrically disposed about ...
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WO/2004/073760A1 |
The invention relates generally to a coating composition for a polymeric surface, methods for coating a polymeric surface, methods for preparing coated medical devices, polymeric surfaces coated with the coating composition, and medical ...
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WO/2004/073762A1 |
The invention relates to the use of a zwitterionic detergent in order to reduce complement activation on a plastic surface provided with a coating made of an ionic complex of an anionic heparin or heparin derivative and cationic surfacta...
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WO/2004/069298A1 |
The invention relates to the use of basic fibroblast growth factor (FGF-2) derived proteins being chosen among FGF-2 mutants which are unable to interact specifically with the Translokin, for the preparation of biomaterials or devices ch...
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WO/2004/060428A1 |
Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
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WO/2004/054473A1 |
Medical devices and methods of producing same are provided. The medical device comprising a body member and a coating on at least a portion of the body member comprising a polyalkylene oxide and a functional group, preferably heparin, ma...
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WO/2004/043503A1 |
The invention aims at providing a safe and efficacious hemostatic and relates to a bioabsorbable synthetic nonwoven fabric characterized in that thrombin as the active ingredient is fixed to thereto and a hemostatic consisting of the sam...
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WO/2004/037310A2 |
Coatings comprising protein resistant components and therapeutic components on medical devices are disclosed. The coatings act to down-regulate complement activation. Medical devices can be coated with these coatings to prevent side effe...
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WO/2004/028406A1 |
A stent having a multi−layered coating adhered to its surface which can prevent restenosis and thrombosis at the implant site. The stent coating is comprised of two layers. The first layer is a polymeric coating with one or more biolog...
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WO2002038649A9 |
A polyamide and a process for preparing the polyamide are disclosed. The process comprises reacting in a reaction mixture a monomer selected from unsaturated carboxylic acids, esters of unsaturated carboxylic acids, anhydrides of unsatur...
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WO/2004/017892A2 |
Drug eluting coating compositions are composed of at least one therapeutic agent dispersed in modified, biologically active binders. The therapeutic agents included in the coating composition are paclitaxel, sirolimus, tacrolimus, everol...
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WO/2004/018085A1 |
A modified substrate comprising a hydrophilic polymer in which the amount of soluble hydrophilic polymers contained is 15 wt.% or less and to which the sticking of human platelets amounts to 10 platelets / 4.3 x 103 μm2 or less; and a p...
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WO/2004/015096A2 |
The invention relates to a stable destabilase complex in the form of a monomer, which is capable of aggregating into a polymer destabilase complex forming a liposome and which can be obtained from medicinal leeches using the following me...
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WO/2004/009147A1 |
Implantable medical devices having an anti-restenotic coatings are disclosed. Specifically, implantable medical devices having coatings of proteintyrosine kinase inhibitors are disclosed. The anti-restenotic protein-tyrosine kinase inh...
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WO2002060509A9 |
A method of modifying surfaces of a device, for example, a medical device, is disclosed. The method includes modifying a surface of a device by providing a device, exposing the device to a reactive gas and plasma energy to create a plasm...
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WO/2004/009148A1 |
The invention relates to a coating composition for an implantable medical device, which contains at least one polymer and at least one biologically active substance, i.e. naphthazarin and/or a naphthazarin derivative, particularly Shikonin.
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WO/2004/006978A1 |
An apparatus and process for coating a plurality of articles in batches, in particular for applying a biocompatible layer on articles adapted to come into contact with blood or body tissue, e.g. a coagulation-preventing substance so as t...
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WO/2004/006977A2 |
This invention relates to coating a surface wherein the coated surface inhibits foulants such as cell and/or protein and/or prion adhesion or formation. In particular, the coated surface may be part of a medical device which inhibits bac...
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WO/2004/004794A1 |
A resin compatible with body fluid and living tissue, which comprises a substituted oxyalkylene polymer represented by the general formula (1) and having a weight-average molecular weight of 1,000 to 1,000,000 and is characterized by bei...
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WO/2004/000924A1 |
The present invention relates to an anti-microbial or anti-coagulating polymer resin and a method for preparing the same, and a medical appliance or instrument using the same, and more particularly to a method for preparing an anti-micro...
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WO/2003/101201A1 |
Methods are provided for enhancing transfection efficiency of bone marrow cells by transfecting early attaching cells derived from bone marrow in culture. Methods are also provided for utilizing such early attaching cells derived from au...
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WO/2003/101989A1 |
The present invention provides a compound of formula (I): or a pharmaceutically acceptable salt thereof. These compounds are inhibitors of protein kinases, particularly inhibitors of JAK and CDK2 mammalian protein kinases. The invention ...
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WO/2003/097117A1 |
An inorganic substrate with two or more coating layers is provided. The first coating layer is attached to the inorganic substrate and includes the polymeric reaction product formed upon hydrolysis of a silane compound having at least tw...
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WO/2003/094991A1 |
The invention relates to the use of polysaccharides containing the sugar structural element N-acylglucosamine for producing haemocompatible surfaces, in addition to methods for coating surfaces in a haemocompatible manner with said polys...
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