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WO/2017/182097A1 |
The present invention relates an improved and well reproducible process for the preparation of Enclomiphene citrate having needle shaped crystal habit, and moreover, it is also related to a solid form of Enclomiphene citrate.
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WO/2017/177326A1 |
The invention provides conjugates that comprise a targeting moiety, a nucleic acid, and optional linking groups as well as synthetic intermediates and synthetic methods useful for preparing the conjugates. The conjugates are useful to ta...
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WO/2017/162476A1 |
An etheramine mixture comprising of at least one amine selected from the group consisting of amine of Formula (I) and amine of Formula (II) wherein R1-R12 are independently selected from H, alkyl, cycloalkyi, aryl, alkylaryl, or arylalky...
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WO/2017/162477A1 |
An etheramine mixture comprising at least 90% by weight, based on the total weight of the etheramine mixture, of an amine of Formula (I) and/or (II), wherein R1-R12 are independently selected from H, alkyl, cycloalkyl, aryl, alkylaryl, o...
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WO/2017/153779A1 |
A lipid comprising a tri-chain cation of formula (la) having a cationic head group and three C12-24 hydrocarbyl groups for use in non-viral gene delivery systems, for example in the formation of lipopolyplex transfection vectors. Excepti...
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WO/2017/155686A1 |
An acyclic fluorinated compound of formula (I) is amine -containing acyclic hydrofluoroethers. The acyclic fluorinated compound is useful as heat transfer, solvent cleaning, fire extinguishing agents and electrolyte solvents and additives.
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WO/2017/151733A1 |
Disclosed herein are transfection complexes comprising at least one cell surface ligand; at least one helper lipid component; and a transfection enhancer. Also disclosed are pharmaceutical compositions comprising the disclosed transfecti...
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WO/2017/147145A1 |
The disclosure provides for coating compositions comprising macrocycles and salts in aqueous buffer and the use of the coating composition to prevent absorption of small molecules into polymeric surfaces.
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WO/2017/141806A1 |
The present invention addresses the problem of providing: a novel ionic compound which can be preferably added to a non-aqueous electrolytic solution for an electrical storage device; a novel non-aqueous electrolytic solution containing ...
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WO/2017/138566A1 |
The present invention provides a triphenylamine derivative represented by general formula (1). (In the formula, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14 and R15 independently represent a hydrogen atom, a substituted or...
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WO/2017/138017A1 |
The present, invention relates to a cost effective, environment friendly industrially viable process for the preparation of 7,8-dimethoxy-1,3-dihydro-2H-3-benzazepine-2-one, an intermediate used in the preparation of ivabradine, without ...
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WO/2017/137047A1 |
The invention relates to a method for arylation of amines, such as aliphatic amines by reaction of aryl-halogens, e.g. chloro- or fluorobenzene derivatives without strongly electron withdrawing substituents in the presence of a strong base.
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WO/2017/137955A1 |
The present invention relates to novel chiral 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop
an-1-amine (5) and racemic 3-(2-(allyloxy)-5-methylphenyl)-N,N-diisopropyl-3-phenylprop
an-1-amine () and its use in improved and ...
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WO/2017/134841A1 |
The present invention provides: a liquid crystal display element that is highly reliable, has improved various characteristics as a liquid crystal display element, and in which dropping marks do not readily occur during production, witho...
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WO/2017/132912A1 |
The present invention provides an alkylamine with a benzoalicyclic substituent and an application thereof. More specifically, the invention relates to a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, a...
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WO/2017/123333A1 |
The present disclosure provides a process for the co-preparation of a polyetheramine and an alkylene amine mixture by aminating a liquid polyol initiator mixture comprising an alkoxylated alcohol and a solid high melting polyol. The poly...
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WO/2017/113439A1 |
Provided are a plating additive for electrodeposition, and the corresponding fabrication method thereof. The plating additive enables to electroplate holes on a substrate with good height uniformity within a feature and among features at...
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WO/2017/100856A1 |
The present invention relates to a novel dendrimer. The present invention also relates to formulations comprising the dendrimer with improved characteristics. For instance, the present invention relates to formulations comprising pestici...
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WO/2017/080770A1 |
The invention relates to the synthesis of tamoxifen, endoxifen and derivatives thereof. Starting from a substituted benzoic acid derivative and 2-phenoxyethyl halide, the intermediate product of general formula (I) is obtained. The compo...
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WO/2017/079965A1 |
The present invention relates to a catalyst for aminating a polyether polyol and preparation method thereof and a method of preparing a polyetheramine using the catalyst. The catalyst has active components and a carrier. The active compo...
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WO/2017/076293A1 |
The invention relates to a method for preparing an oxazolidinone intermediate. Specifically, a synthesis procedure for the intermediate comprises: directly performing a "one-pot" reaction on a compound I, a compound J or a compound L wit...
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WO/2017/070651A1 |
Disclosed is a process for preparing (Z)-endoxifen, comprising (i) recrystallizing an input crystalline solid comprising a mixture of (Z)-endoxifen (1) and (E)-endoxifen (2) from a first solvent to provide a first crystalline solid and a...
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WO/2017/068496A1 |
The present application relates to an improved process for the preparation of Eliglustat or its pharmaceutically acceptable salts thereof. Further relates to isolation of intermediates in the form of solid and their use for preparation o...
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WO/2017/064490A1 |
There is provided a compound of the formula wherein: A represents a phenyl group, a naphthyl group, a biphenyl group or two phenyl groups linked by a C1-C8 alkyl chain; B1 and B2 in each occurrence are independently selected side chains ...
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WO/2017/055067A1 |
The invention relates to a compound of general formula (I) where R1 through R8, x, y, and z are defined as in the description. The invention also relates to an absorbent comprising a solution of the compound, and the use thereof, and a m...
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WO/2017/042514A1 |
The present invention relates to a compound of formula (I): in which: - the R1 and R2 groups, which may be identical or different, are, independently of one another, a saturated or unsaturated, linear, branched or cyclic hydrocarbon grou...
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WO/2017/042099A1 |
The present invention relates to compounds of formula I or pharmaceutically acceptable salt, solvate or hydrate thereof wherein ASC is -N(R8)ASC-1; ASC-1 is C 2-C 5alkylene-N(R9a)R9b or C(=O)-C 1-C 4alkylene-N(R9a)R9b, wherein in alkylen...
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WO/2017/036436A1 |
The present invention provides primin derivatives of general formula II and/or III, wherein R1 is selected from the group consisting of methyl and hydrogen, R2 is selected from the group consisting of methoxy, hydroxy, hydrogen, R3 is se...
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WO/2017/035879A1 |
The present invention provides a method for preparing single-layer metal phosphate and applications thereof. The method comprises: (1) carrying out intercalation treatment on layered metal phosphate by means of alkylol amine, so as to ob...
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WO/2017/024703A1 |
The present invention provides an aromatic amine compound comprising a structure of formula (I). The compound provided according to the invention has luminous efficacy, which will result in, when in a condition of a current density of 20...
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WO/2017/025448A1 |
The invention relates to the use of an amine of formula (I) in a curing agent for epoxy resins, to a curing agent for epoxy resins containing the amine of formula (I) and to resultant epoxy resin compositions which can be used particular...
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WO/2017/016960A1 |
The present invention relates to a process for synthesizing a compound of formula (I), wherein R1 is C1-6alkoxy or haloC1-6alkoxy, R2 is C1-6alkyl unsubstituted or substituted by a substituent selected from C1-6alkoxy and haloC1-6alkoxy,...
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WO/2017/005710A1 |
The present invention relates phenoxyhalogenphenylamidmes of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and also to an agroch...
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WO/2017/002742A1 |
Provided is a photoelectric conversion element having excellent durability against photoirradiation. This photoelectric conversion element has a negative electrode, a positive electrode, an active layer that is provided between the negat...
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WO/2016/202742A1 |
The present invention relates to halogen-substituted phenoxyphenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and ...
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WO/2016/202808A2 |
The present invention relates to a process for the synthesis of tapentadol intermediates comprising the following route of synthesis: (I) → (II) → (III) → (IV) → (V).
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WO/2016/202688A1 |
The present invention relates to halogen-substituted phenoxyphenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and ...
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WO/2016/200827A1 |
A compound, or a pharmaceutically acceptable salt thereof, having a formula I of: (I) wherein Ar is an arylene or heteroarylene; R1 has a structure of: (II) wherein W is an alkanediyl, alkenediyl, a carbonyl, or a combination thereof; X ...
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WO/2016/193220A1 |
The present invention relates to a method for changing the pigmentation of a skin, a mucous membrane or hair with a compound of general formula (I), a cosmetic use of said compound of general formula (I), to cosmetic compositions compris...
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WO/2016/181292A1 |
The present invention relates to a process for the preparation of 5-(3,4-dimethoxyphenylethyl) methyl-amino-2-(3,4-dimethoxyphenyl)-2-isopropyl valeronitrile, which is known as Verapamil. The present invention also relates to a process f...
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WO/2016/177307A1 |
Among others, the present invention provides isocyanate resin compositions which include an isocyanate compound containing two or more isocyanate functional groups; a chain extender comprising a degradable diamine and optionally a dihydr...
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WO/2016/169477A1 |
Disclosed are a Y-type polyethylene glycol derivative and a preparation method therefor. The present invention has the advantages of determined molecular weights and the number of chains and can avoid the defects of nonuniformity of a PE...
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WO/2016/166921A1 |
[Problem] The purpose of the present invention is to provide an asymmetrical diamine suited to the production of polyimide, and a method for producing the asymmetrical diamine. [Solution] The present invention provides a compound represe...
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WO/2016/145479A1 |
The present invention relates to novel compounds and their use in the prophylactic and/or therapeutic treatment of fibrosis and fibrosis-related conditions.
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WO/2016/149488A1 |
The present disclosure relates to tertiary amine co-initiators that demonstrate reduced leaching and which may be utilized in dental restoration and other biomedical applications. Embodiments of the present disclosure provide compounds a...
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WO/2016/142126A1 |
The invention relates to novel nitrogenous compounds pertaining to the family of tertiary polyether alkanolamines of general formula (I) wherein x is a whole number between 0 and 10, R1 is independently selected from an alkyl radical com...
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WO/2016/140302A1 |
The present invention provides a polyimide precursor in which the quantity of radicals generated is relatively large. Through this polyimide precursor, reaction of a polymerizable compound is accelerated, the pretilt angle in liquid crys...
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WO/2016/140232A1 |
The present invention pertains to a peptide synthesis reaction using a carrier which can reversibly repeat a dissolved state and an encapsulated state, wherein it is easy to solve the problem of amino acid active species which are presen...
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WO/2016/140358A1 |
The purpose of the present invention is to provide a catalyst composite body which has an excellent reducing action. The above-described problem is able to be solved by a catalyst composite body according to the present invention, which ...
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WO/2016/140245A1 |
The present invention addresses the problem of providing a curable composition whereby a cured material having a low Abbe number and increased durability can be fabricated, and of providing a curable composition in which increasing of th...
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