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Patent Searching and Data


Matches 1,001 - 1,050 out of 10,495

Document Document Title
WO/2006/037480A1
The invention is concerned with hexafluoroisopropanol substituted ether derivatives of formula (I), wherein Rl to R3 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. The...  
WO/2006/034605A1
The present invention relates to azabicyclic ring ammoniums of general formula I in which the definition of each radical is described in the specification and/or their pharmaceutically acceptable salts and hydrates; pharmaceutical compos...  
WO/2006/034277A1
The present invention provides bicyclic beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer’s disease.  
WO/2006/034296A2
The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer’s disease.  
WO/2006/032165A1
The present invention relates to 5-Membered-N-heterocyclic compounds of formula (I), and/or the salts and the hydrates thereof; and to the pharmaceutical compositions comprising such compounds, and the use of such compounds in treatment ...  
WO/2006/032322A1
The present invention relates to compounds of the general formula (I) and salts and physiologically functional derivatives thereof, (I) wherein R1 is independently hydrogen, alkyl, cycloalkyl, hydroxyalkyl, haloalkyl, haloalkyloxy, aryl,...  
WO/2006/030211A2
Compounds of formula: (I) are found to antagonise N-type calcium channels wherein: - A is a 5- to 10-membered heteroaryl or heterocyclyl moiety, said moiety being optionally fused to a phenyl, 5- to 6-membered heteroaryl, C3-C6 carbocycl...  
WO/2006/030753A1
A new medicinal use of E-4-[4-(5-methyl-2­phenyl-4-oxazolylmethoxy)benzyloxyimino] -4-phenylbutyric acid, Z-2-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl­oxyimino ]-2-(4-phenoxyphenyl)acetic acid, 2-[2-propyl-3­[3-[2-ethyl-4-(4-flu...  
WO/2006/027788A1
The invention relates to a process for the preparation of N-carboxyanhydrides by reaction of the corresponding amino acid with phosgene, diphosgene and/or triphosgene in a solvent medium, characterized in that the reaction is a least par...  
WO/2006/028972A2
Mercaptoamide compounds, represented by Formulas (IA), (IB), (IIA), and (IIB): or a pharmaceutically acceptable salt thereof, inhibit histone deacetylase enzyme and are useful for the treatment and/or prevention of various infections, ca...  
WO/2006/028963A2
The present invention relates to substituted heterocyclic compounds and compositions comprising a substituted heterocyclic compound. The present invention also relates to methods for preventing or treating various diseases and disorders ...  
WO/2006/026316A2
This invention provides estrogen receptor modulators of formula I, having the structure (I) wherein Q1 Q2, R1, R2 R2a, R3,R3a, and X as defined in the specification, or a pharmaceutically acceptable salt thereof.  
WO/2006/021420A3
The invention relates to a method for producing diarylcycloalkyl derivatives of general formula (I), wherein the radicals have the indicated meanings. The invention further relates to novel intermediate products that are formed by means ...  
WO/2006/021420A2
The invention relates to a method for producing diarylcycloalkyl derivatives of general formula (I), wherein the radicals have the indicated meanings. The invention further relates to novel intermediate products that are formed by means ...  
WO/2006/022794A1
The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of tricyclic compounds that are useful as such age...  
WO/2006/018115A1
The invention relates to compounds of formula (I), wherein R1 represents H, (C1-C6)-alkyl; R2 represents H, an O-(C1-C3)-alkyl, CF3; or R1 and R2 represent, together with the phenyl-ring, a condensed naphthyl; R3 represents a (C1-C6)-alk...  
WO/2006/018118A1
The invention relates to compounds of formula (I), wherein R represents H, CF3; R1 represents H, CF3, a (C1-C6)-alkyl, a phenyl, a phenoxy; R2 represents H, a (C1-C4)-alkyl, O-(C1-C4)-alkyl, CF3; or R1 and R2 represent, together with the...  
WO/2006/018116A1
The invention relates to aryl-cycloalkyl substituted alkanoic acid derivatives in addition to the physiologically compatible salts thereof and physiologically functional derivatives. The invention also relates to compounds of formula (I)...  
WO/2006/019833A1
The present invention discloses novel aryl oxazole compounds of Formula I (I), or pharmaceutically acceptable salts thereof, which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing and us...  
WO/2006/016399A1
A compound which inhibits the production of IL-6 and/or TNF&agr by inflammatory cytokines and is useful in the prevention of or treatments for diseases such as various inflammatory diseases in which these cytokines participate and autoim...  
WO/2006/014134A1
Compounds of formula: (chemical formula to be inserted here - please see paper copy) wherein Ar1 is as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepar...  
WO/2006/014015A1
Unsaturated aminodiols useful as the raw material in the synthesis of sphingomyelin effective for drug delivery systems or the like can be produced through easy and general means by reacting an unsaturated aminodiol represented by the ge...  
WO/2006/014357A1
Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atheros...  
WO/2006/014413A1
Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atheros...  
WO/2006/010968A1
The new aryloxy acetic acid amide derivatives of formula (I) where R1 and R2 are the same or different and can be hydrogen atom or C1-4 alkanoylamido group optionally substituted by halogen atom or C1-4 alkyl-sulfonylamido group or N'-( ...  
WO/2006/011466A1
Disclosed are a compound and pharmaceutically acceptable salts thereof represented by the general formula (1) below. (In the formula (1), R1, R2, R3, R4 and X are the same as R1, R2, R3, R4 and X defined in the description.)  
WO/2006/008754A1
The present invention provides a novel process for preparation of 5­aminomethyl substituted oxazolidinones, key intermediates for oxazolidinone antibacterials including linezolid. Thus, the key intermediate of linezolid is prepared by a...  
WO/2006/009134A1
A novel fungicide that exhibits a wide disease control spectrum against pathogenic fungi acting on various crops and helps resolve worsening resistant strain problems. There are provided diamine derivatives of the formula (1), a process ...  
WO/2006/006832A1
The present invention relates to a novel sulfamide derivative, a pharmaceutically acceptable salt thereof and a pharmaceutical composition for upregulation of lipid metabolism comprising same as an active ingredient.  
WO/2006/003495A1
The present invention is directed at substituted heteroaryl- and phenylsulfamoyl compounds, pharmaceutical compositions containing such compounds and the use of such compounds as peroxisome proliferator activator receptor (PPAR) agonists...  
WO/2006/004180A1
A method for producing an optically active cyclopropanecarboxylate compound represented by the following formula (5): (wherein R6, R7, R8, R9 and R10 are as defined below) is disclosed which is characterized by reacting an olefin represe...  
WO/2006/004215A1
Benzoxazoles represented by the general formula (1) and being useful as herbicides: wherein R1 to R4 are each H, halogeno, NO2, CN, C1-4 alkyl, C1-4 haloalkyl, C1-4 haloalkoxy, C2-5 alkanoyl, formyl, C2-6 alkoxycarbonyl, or carboxyl; R5 ...  
WO/2006/004922A1
The present invention provides a novel crystalline form of linezolid referred to herein as Form IV as well as methods for the preparation and use of Form IV. The present invention provides pharmaceutical compositions that comprise therap...  
WO/2006/000323A1
The invention is concerned with novel hexafluoroisopropanol derivatives of formula (I), wherein R1 to R6, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These ...  
WO/2005/123703A3
The present invention relates to novel compounds of formula (I) wherein W, n, X and W’ are defined in the description; invention compounds are modulators of metabotropic glutamate receptors - subtype 5 (“mGluR5”) which are useful f...  
WO/2005/123050A2
The present invention provides a method for treating a thrombotic or an inflammatory disorder administering to a patient in need thereof a therapeutically effective amount of at least one compound of Formula (I) or Formula (V): (I) [INSE...  
WO/2005/123702A1
Disclosed are (2S)-2-&lcub 1-[(1S)-1-Isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylca rbamoyl]-cyclopentylmethyl&rcub -4-methoxy-butyric, Potassium-(2S)-2-&lcub 1-[(1S)-1-Isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylca rbamoyl]-cycl...  
WO/2005/123703A2
The present invention relates to novel compounds of formula (I) wherein W, n, X and W’ are defined in the description; invention compounds are modulators of metabotropic glutamate receptors - subtype 5 (“mGluR5”) which are useful f...  
WO/2005/123050A3
The present invention provides a method for treating a thrombotic or an inflammatory disorder administering to a patient in need thereof a therapeutically effective amount of at least one compound of Formula (I) or Formula (V): (I) [INSE...  
WO/2005/121130A2
This invention relates to compounds of the Formula (I) or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, TNF-&agr or combinati...  
WO/2005/120515A2
Disclosed herein are carbonyl compounds of having the structural formula (I) or a pharmaceutically acceptable salt, amide, ester, or prodrug thereof, Methods and compositions are disclosed for treating disease states including, but not l...  
WO/2005/118561A1
The present invention relates to benzoxazolone derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals, in the treatment of movement disorders, in particular in Parkinson's ...  
WO/2005/118543A1
A compound represented by the general formula (I): [wherein A represents optionally substituted amino or a group represented by the formula (II) (wherein ring A1 represents an optionally substituted nitrogenous heterocyclic group); D rep...  
WO/2005/118511A2
Compounds, compositions and methods are provided for stabilizing transthyretin and for treating, preventing, or ameliorating one or more symptoms of transthyretin mediated diseases. In one embodiment, the compounds are biphenyls and rela...  
WO/2005/117817A1
The invention relates to an agent for dying keratin fibers, particularly human hair, containing, in a cosmetically acceptable carrier and in the form of coupler components, at least one m-phenylene diamine derivative of general formula (...  
WO/2005/116016A1
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of the Peroxisome Proliferator-Activated R...  
WO/2005/115983A1
Aryl sulfonamide and sulfonyl compounds of formula (I) as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.  
WO/2005/115999A1
The present invention relates to compounds of general formula I, and racemic mixtures, optically active isomers, pharmaceutically acceptable salts or solvates thereof, in which the definition of each radical is described in the claims, a...  
WO/2005/115998A1
The invention provides compounds of the general formula (I), racemic mixtures, optical isomers, pharmaceutically acceptable salts, solvates and pharmaceutical compositions thereof. The definitions of substituents in the general formula (...  
WO/2005/115148A1
Compounds of formula (I) are described: along with compositions thereof, methods of use thereof (particularly as fungicides), and methods of making the same.  

Matches 1,001 - 1,050 out of 10,495