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Matches 1 - 50 out of 17,739

Document Document Title
WO/2019/049946A1
The present invention provides a photoelectric conversion element which has excellent photoelectric conversion efficiency even in cases where a photoelectric conversion film is a thin film. The present invention also provides a photosens...  
WO/2019/044946A1
A method for producing a compound represented by formula (C), the method comprising a step for converting a compound represented by formula (B) (wherein R1 represents an amino group protected by a protecting group) by intramolecular cycl...  
WO/2019/046316A1
The present invention relates to compounds of formula (I) (shown below) useful as inhibitors of phosphatidylinositol- 3 -phosphate 5-kinase (PIKfyve) as well as their use for treating diseases and disorders associated with PIKfyve.  
WO/2017/040772A9
The invention provides compounds of Formula 1: or a stereoisomer, pharmaceutically acceptable salt, or mixture thereof; and methods of making and using such compounds. The invention includes pharmaceutical compositions containing such co...  
WO/2019/043372A1
There are described compounds of formula (I) in which X, R1, R2 and n are each as herein defined; and their use as a medicament in the treatment of conditions involving abnormal activation and/or malfunction of the hedgehog pathway, such...  
WO/2019/043373A1
There are described compounds of formula (I) in which R1, R2, R3,R4 and R5 are each as herein defined; and their use as a medicament in the treatment of conditions involving abnormal activation and/or malfunction of the hedgehog pathway,...  
WO/2019/039888A1
The present invention relates to a real-time fluorescence imaging sensor for measuring glutathione in organelles and a preparation method therefor. More particularly, the present invention relates to a novel compound for measuring glutat...  
WO/2019/037861A1
Compounds of formula (I) wherein A, R, W1, W2, W3, W4, W5, W6, L, Q, Rx and u have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.  
WO/2019/039429A1
This pest control agent contains a compound represented by a formula (I) (in the formula: Ar denotes a substituted or unsubstituted C6-10 aryl group; R1 denotes a cyano group or a substituted or unsubstituted thiocarbamoyl group; R2 deno...  
WO/2019/037742A1
Disclosed in the present invention are an imidazolone androgen receptor antagonist, a preparation method therefor and use thereof. The imidazolone androgen receptor antagonist of the present invention has a structure represented by formu...  
WO/2019/040825A1
Conformationally restricted cyanine fluorophores, as well as methods of making and using the compounds, are described. The conformationally restricted cyanine fluorophores have a chemical structure according to Formula (I), or a stereois...  
WO/2019/034686A1
The present invention relates to compounds of formula (I): Formula (I) wherein Q is selected from O or S; R1 is a saturated or unsaturated, optionally substituted hydrocarbyl group optionally including one or more heteroatoms N, O or S; ...  
WO/2019/035985A1
The present disclosure provides crystalline polymorphic forms of TG02 free base and TG02 acid addition salts, pharmaceutical compositions comprising crystalline polymorphic forms of TG02 free base and TG02 acid addition salts, and method...  
WO/2019/036377A1
The present disclosure provides certain tricyclic compounds that are histone methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of G9a and/or GLP such as cancers an...  
WO/2019/036384A1
The present disclosure provides tricyclic compounds of formula (I) that are histone methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of G9a and/or GLP such as can...  
WO/2019/029521A1
The present application belongs to the field of medicine. In particular, the present application relates to a diarylthiohydantoin compound as an androgen receptor antagonist or a pharmaceutically acceptable salt thereof, a preparation me...  
WO/2019/029408A1
Provided are a streptovaricin derivative, a preparation method therefor, and an application thereof, pertaining to the field of bio-pharmaceuticals. The novel streptovaricin derivative 1-4 is obtained by using Streptomyces spectabilis XW...  
WO/2019/027765A1
Disclosed are new small molecules having a substituted pyrimidine or substituted fused pyrimidine core structure and the uses thereof for modulating glucocerebrosidase activity. Also disclosed are pharmaceutical compositions comprising t...  
WO/2019/027163A1
Disclosed are: a compound represented by chemical formula 1; an organic electric element comprising a first electrode, a second electrode, and an organic material layer between the first electrode and the second electrode; and an electro...  
WO/2019/025562A1
The present invention provides dihydrooxydiazinone compounds of general formula (I) : in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, ph...  
WO/2019/021059A1
The present disclosure provides a compound of formula (I): or a pharmaceutically acceptable salt thereof, and its therapeutic uses for activating a growth factor pathway, promoting wound healing, promoting tissue repair, and treating hea...  
WO/2019/021945A1
Provided are: a compound represented by formula I; a new photoreactive compound that can be used in nucleic acid photoreaction techniques by a photoreactive crosslinking agent comprising the compound; and a photoreactive crosslinking age...  
WO/2019/022435A1
Disclosed are: a compound represented by chemical formula 1; an organic electronic device comprising a first electrode, a second electrode and an organic layer between the first electrode and the second electrode; and an electronic appar...  
WO/2019/022158A1
Provided are a compound represented by formula I that can be used in nucleic acid photoreaction techniques, and a photoreactive crosslinking agent comprising the compound.  
WO/2019/022061A1
This fungicide for agricultural and horticultural use includes a compound represented by formula (I) (in the formula, X represents a halogen group, etc.; n represents any integer of 0-4; when n is 2 or higher, X may be the same or differ...  
WO/2019/022637A1
The invention relates to the chemistry of organic heterocyclic compounds and more particularly to a new quaternary ammonium salt containing a fragment of a vitamin B6 derivative of formula I and exhibiting antibacterial, antimycotic, ant...  
WO/2019/018890A1
The present invention relates to new spirocyclic compounds that may be useful in as anti- cancer and anti-microbial agents, to the preparation of the compounds, and to compositions including the compounds. The present invention also rela...  
WO/2019/022223A1
The present invention addresses the problem of providing a novel compound which has a retinoid-related orphan receptor γ antagonistic activity and exhibits a therapeutic effect or a prophylactic effect on an autoimmune disease such as m...  
WO/2019/017730A1
The present invention provides a novel heterocyclic compound and an organic light-emitting device using same.  
WO/2019/015545A1
Disclosed is a method of preparing hernandezine from 5-bromotetrandrine. Also disclosed is a method of preparing hernandezine by using tetrandrine as a raw material, wherein the tetrandrine is subjected to bromination and methoxylation t...  
WO/2019/017734A1
The present invention provides a novel heterocyclic compound and an organic light-emitting device using same.  
WO/2019/017731A1
The present invention provides a novel heterocyclic compound and an organic light-emitting device using same.  
WO/2019/017741A1
The present invention relates to a compound and an organic light-emitting diode comprising the same.  
WO/2019/014305A1
Substituted benzoxazole and benzofuran chemical entities of Formula (I): wherein, V, W, X, Y, Z, and m have any of the values described herein and compositions comprising such chemical entities; processes for making them; and their use i...  
WO/2019/013312A1
The present invention provides a compound represented by formula (I). (In formula (I), (2) is, for example, (3); R1 is a hydrogen atom; R2a and R2b have been bonded to each other to form a ring B, which is (5); R3a is a hydrogen atom; R3...  
WO/2019/013311A1
The present invention provides a compound represented by formula (I). (I) (In the formula: (2) is (3) or the like; y is 0 or 1; R1 is hydrogen or the like; R2a and R2b combine with an adjacent carbon atom to form ring B; ring B is a subs...  
WO/2019/014308A1
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This inve...  
WO/2019/007866A1
The invention relates to a composition comprising an electron-transporting host and a hole transporting host, to the use thereof in electronic devices and electronic devices containing said composition. The electron-transporting host is ...  
WO/2019/009412A1
The present invention addresses the problem of providing a novel compound having high LSD1 inhibitory activity, high selectivity for LSD1 inhibition, and/or having useful therapeutic effects for various diseases. One embodiment of the pr...  
WO/2019/010014A1
The present disclosure teaches the use of a dual-acting opioid agonist for the treatment of pain (e.g., inflammatory pain). The opioid agonist activates both the kappa and delta opioid receptors to provide synergistic reduction in pain. ...  
WO/2019/009249A1
The present invention provides a photoelectric conversion element that has a photoelectric conversion film having excellent suitability for vapor deposition and that exhibits excellent photoelectric conversion efficiency even in a case w...  
WO/2019/003148A1
Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases. F...  
WO/2019/000494A1
Provided is a fluorene-based organic electroluminescent compound, having the following structure: The compound has good thermal stability, high luminous efficiency, and high luminous purity, and can be used for manufacturing organic elec...  
WO/2019/006002A1
The present invention provides, inter alia, compounds capable of inhibiting NF-κB. Pharmaceutical compositions containing and methods of using the compounds are also provided herein. Also provided are methods and kits for treating cance...  
WO/2019/004614A1
The present invention provides a novel heterocyclic compound and an organic light emitting element using same.  
WO/2019/001420A1
Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.  
WO/2018/234926A1
A novel organic compound is provided. That is, a novel organic compound that is effective in improving the element characteristics and reliability is provided. The organic compound has a benzofuropyrimidine skeleton or a benzothienopyrim...  
WO/2018/234805A1
The present invention relates to compounds of formula (I). The compounds may be used to modulate the Stimulator of Interferon Genes (STING) protein and thereby treat diseases such as cancer and microbial infections.  
WO/2018/234343A1
Compounds of Formula (0), and stereoisomers and pharmaceutically acceptable salts thereof, as well as methods of use as Interleukin-1 Receptor Associated Kinase (IRAK4) inhibitors are described herein.  
WO/2018/235838A1
The purpose of the present invention is to provide a compound that can be useful for prevention of, or therapy for, constipation and the like. The present invention provides: a compound represented by formula (I) (refer to the descriptio...  

Matches 1 - 50 out of 17,739