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WO/2010/051773A1 |
Disclosed herein are methods of determining the sequence and/or positions of modified bases in a nucleic acid sample present in a circular molecule with a nucleic acid insert of known sequence comprising obtaining sequence data of at lea...
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WO/2010/052939A1 |
Disclosed is a method for detecting a set of at least two epitopes in an allergen. In the method, for detecting the epitopes in the allergen or candidates for the epitopes, a test sample group which is derived from multiple allergy-posi...
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WO/2010/050439A1 |
Disclosed is an NTA immobilization carrier which includes a chitosan immobilized on a carrier and a nitrilotriacetic acid (NTA) which is bound to the chitosan, wherein the NTA immobilization carrier is able to bind a polyhistidine-contai...
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WO/2010/050208A1 |
A liquid flow path device configured in such a manner that a liquid flow path can be easily set from a closed state to an open state. A liquid flow path device, wherein a liquid flow path (12) in which liquid consisting of a sample and/...
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WO/2010/048631A2 |
Systems, devices, and methods for automating laboratory protocols utilizing modular processing components to allow systems to be reconfigured for processing a wide variety of disparate laboratory protocols are provided. In one aspect, a ...
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WO/2010/044598A2 |
Provided is a microfluidic device including: a sample chamber; at least one analyzing unit receiving a sample from the sample chamber and detecting components contained in the sample according to a reaction of the sample and a reagent; a...
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WO/2010/044282A1 |
Provided is an immobilization device for fitting the connecting member of a chip together with the connecting member of a cover whereby the spatial clearance that is formed between the chip and cover is small. The immobilization device c...
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WO/2010/038408A1 |
A reaction container provided with a flow path and a containing section communicating with the flow path and containing liquid introduced into the flow path, wherein, without water repellent surface treatment, the liquid in the containin...
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WO/2010/038897A1 |
An analytic instrument (1) is provided with a channel (20) for moving a sample, and a reservoir (20F) for holding the sample, and has a first member (2) and a second member (3) bonded together by means of a solvent. The analytic instrum...
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WO/2010/036736A2 |
A flow cell device includes a body having a hollow bore in which a liquid sample may reside. An electromagnetic beam may be directed through the body and into the bore to irradiate the liquid sample. The beam may be directed orthogonal t...
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WO/2010/032846A1 |
To develop a method for patterning a biocompatible polymer, which inhibits the non-specific adsorption of a biological material, on a substrate including the inside of a channel of a microchannel device at a high accuracy of the micron l...
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WO/2010/032945A2 |
Provided are a method for immobilizing biomolecules on a solid surface through a cholesteryl group, a device for detecting biomolecules containing both a solid surface and a capture probe immobilized on the solid surface through a choles...
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WO/2010/032805A1 |
Disclosed is a flow sensor (52) that causes a gas (80) mixed in a liquid (81) to move inside a pipe (56) and measures the flow rate of the sample by detecting the gas (80). The flow sensor (52) is configured so that the area of the gas i...
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WO/2010/032595A1 |
Disclosed is a process for simultaneously producing a large quantity of various molecular or particle clusters having any distribution profile and distribution density. A suspension which contains an object material and has one concentr...
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WO/2010/027003A1 |
Disclosed is a detection method for detecting a specific cell in a sample containing multiple cells including the specific cell. Specifically disclosed is a detection method for detecting a specific cell in a sample containing multiple ...
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WO/2010/022519A1 |
In a single-use handheld diagnostic test device and an associated system and method, a biological and/or environmental test sample is received and reacted with reagents. The test device tests a single sample and includes a sensor to dete...
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WO/2010/024197A1 |
A microchip for conveniently measuring blood characteristics in a state as close as possible to the in vivo situation. A microchip (2) for blood analysis to be employed in a blood analysis system (1) for measuring blood characteristics ...
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WO/2010/024123A1 |
A reactor having a cylindrical mixing channel is provided in which, when multiple fluids respectively containing different substances are mixed and reacted, a radially multilayered flow is formed in the channel to synergistically produce...
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WO/2010/022564A1 |
Disclosed herein is a surface functionalized poly(dimethylsiloxa ne) (PDMS) and methods for making the same. The surface functionalized poly(dimethylsiloxane) (PDMS) disclosed herein is applicable in the general field of microfluidics, b...
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WO/2010/021264A1 |
A microchannel chip is produced while preventing a resinous film from sagging into the channel. The chip hence inhibits a liquid specimen from residing therein. With the chip, quantitativeness and reproducibility are heightened. A proc...
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WO/2010/021263A1 |
A microchip (1) in which a resinous film can be inhibited from sagging into a channel. The microchip (1) comprises: a resinous base (2) having a channel groove formed therein; and a resinous film bonded to that side of the base on which...
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WO/2010/018870A1 |
Disclosed are: a polypeptide marker for diagnosing arteriosclerosis; a gene marker for diagnosing arteriosclerosis; an antibody; a probe for detecting an arteriosclerosis marker gene; a DNA microarray or a DNA chip for detecting an arter...
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WO/2010/016303A1 |
Disclosed is a plate-shaped resin substrate having a very fine channel formed on one surface, and one or more cylindrical parts on the other surface, which protrude in a direction substantially orthogonal to the other surface. Through-h...
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WO/2010/016371A1 |
Provided are microchip manufacturing method and manufacturing device capable of preventing a reduction in productivity. In the manufacturing method, a microchip manufacturing device (5) by which two resinous substrates (10, 20) are ther...
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WO/2010/016370A1 |
Provided are microchip manufacturing method and manufacturing device capable of preventing a reduction in the dimensional accuracy of a microchip. The manufacturing method and manufacturing device use, as resinous substrates (10, 20), t...
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WO/2010/016359A1 |
A microchip which comprises: a resinous base having a plurality of fine channels formed on one side thereof, one or more cylindrical parts disposed so as to protrude from the other side, and a through-hole which pierces each cylindrical ...
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WO/2010/016431A1 |
A system and method are provided for selectively functionalizing a transducer microarray. The method provides a microarray including a field of transducers exposed to a shared local environment. A difference in the pH associated with the...
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WO/2010/016916A2 |
A method for creating a removable barrier in a microfluidic apparatus is carried out by: (a) providing a microfluidic apparatus having at least a first chamber and a second chamber, each including at least an inlet, wherein the first and...
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WO/2010/016372A1 |
Provided is a microchip having a protrusion to which a device for introducing or discharging a liquid sample, a device for causing the liquid sample to flow, or another device is connected, the protrusion retaining strength. The microch...
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WO/2010/016399A1 |
Provided is a method for fabricating a microchip, having a projection on the surface thereof, uniformly with a strong bonding strength, and also provided are an apparatus for fabricating, and a microchip fabricated by the method. The app...
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WO/2010/013337A1 |
It is intended to provide a novel reaction device and a method whereby a reaction can be efficiently achieved by using a sample in a minor amount with the use of a capillary which has a probe molecule that is capable of inducing a specif...
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WO/2010/013704A1 |
Provided is a microdevice capable of performing analysis quickly and at a high level of sensitivity even when a minute amount of sample liquid is used. The microdevice is equipped with a rotating substrate, a reaction field provided on t...
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WO/2010/013335A1 |
It is intended to provide a novel reaction device and a method whereby a reaction can be efficiently achieved by using a sample in a minor amount with the use of a capillary which has a probe molecule that is capable of inducing a specif...
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WO/2010/013312A1 |
It is intended to provide a novel microreactor, whereby feed of a liquid located at an arbitrary position in a device can be highly accurately controlled and liquids can be effectively mixed together, and techniques relating thereto. Nam...
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WO/2010/013334A1 |
It is intended to provide a novel reaction device and a method whereby a binding reaction can be achieved within a short throughput time by using a capillary, which has a probe molecule that is capable of inducing a specific binding reac...
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WO/2010/010904A1 |
Disclosed is a microchip (1) provided with: a translucent member (11); a channel (10) or a cell formed on the light incoming side of the translucent member (11); and an aperture (16) formed at a position which corresponds to the channel ...
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WO/2010/010805A1 |
To analyze blood by more accurately simulating the inside of a blood vessel than in the existing methods. A microchip for analyzing blood (2) which is to be equipped in a blood analysis system for measuring the properties of blood (1) a...
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WO/2010/007733A1 |
Disclosed is an analyzing device, wherein an operation cavity (245) is arranged adjacent circumferentially of a rotational drive to a first reserving cavity (243) for reserving a sample liquid, wherein a connecting section (255) is dispo...
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WO/2010/005000A1 |
A disc for clinical examination comprising a disc-shaped disc main body and at least one cell formed on the disc main body, wherein the cell is provided with a specimen reservoir which is formed on the disc main body and provided with a ...
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WO/2010/001636A1 |
The width of a reaction flow passage (365) of a mini-array (350b) is formed so as to gradually increase from a first connection port (361) toward a first spot area (366a). The depth of the reaction flow passage (365) is constructed such ...
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WO/2010/001923A1 |
Disclosed is a novel means for detecting the sensitivity to isoniazid (INH) in a tubercle bacillus, i.e., for determining whether or not a tubercle bacillus is an INH-resistant bacterium, more reliably. Specifically disclosed is a metho...
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WO/2010/001924A1 |
Disclosed is a novel means for detecting the sensitivity to isoniazid (INH) in a tubercle bacillus, i.e., for determining whether or not a tubercle bacillus is an INH-resistant bacterium, more reliably. Specifically disclosed is a metho...
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WO/2010/001876A1 |
Disclosed is a biochip substratum for immobilizing thereon a probe comprising a biological substance (e.g., a protein, a nucleic acid), wherein the biochip substratum can immobilize the probe at a high immobilization ratio and a uniform ...
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WO/2010/001023A2 |
The clamp comprises first and second arms (76, 78) able to move relative to one another along a gripping direction (Z) between a first position of gripping, and a first position of releasing, the first biological sample holder (10). The ...
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WO/2009/157251A1 |
Disclosed is a novel means whereby integration dysfunction syndrome can be highly accurately and objectively diagnosed with the use of the blood of a patient as a sample. A method of detecting integration dysfunction syndrome with the us...
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WO/2009/157211A1 |
A method of measuring the activity of cultured cells which comprises a dividing procedure and a measuring procedure. By the dividing procedure, a microchamber surrounding the cells to be measured is located in a culture container contai...
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WO/2009/157327A1 |
To selectively regulate an extension reaction within a desired area in a substrate. An oligo probe provided with a caged compound at the terminus thereof is immobilized to a reaction area in a substrate. After pouring a reaction solutio...
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WO/2009/145022A1 |
Provided is a microtip having a microchannel that prevents adsorption of a sample, such as a protein, onto the microchannel, while also preventing sample loss caused by adsorption and problems such as channel blockage. The microtip is a ...
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WO/2009/145333A1 |
Disclosed is a unit for detecting the interaction of biological molecules using a carrier whereon the biological molecules are affixed. The unit has a hollow holder that has an open part at one end, the other end of which is closed, and ...
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WO/2009/142257A1 |
Disclosed is a composition, a kit or a DNA chip for use in the diagnosis of esophageal cancer, which comprises multiple polynucleotides selected from the group consisting of polynucleotides of which expression levels in an esophageal can...
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