Title:
化学化合物
Document Type and Number:
Japanese Patent JP2009511459
Kind Code:
A
Abstract:
Compounds of formula (Ia) are found to be active in inhibiting replication of flaviviridae viruses (Ia), wherein R1 and R2 are the same or different and represent hydrogen, halogen, -L-O-R3, -L-O-L-A or -L-O-L'-A', wherein each L is the same or different and represents a direct bond or a C1-C4 alkylene group; L' represents a direct bond or a C2-C4 alkylene group; R3 represents hydrogen, C1-C4 alkyl or C1-C4 haloalkyl; A represents a 5- to 10-membered heterocyclyl group; and A' represents a C6-C1 aryl group; wherein at least one of R1 and R2 is -L-O-R3, -L-O-L-A or -L-O-L'-A'.
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Inventors:
Matthews, Neil
Alexander James Floyd, Thomas
Keith Charles, Spencer
Denison, Helena
Bernes, Michael Christopher
Chana, Slinder Thing
Genens, Lynn
Pilkington, Christopher John
Alexander James Floyd, Thomas
Keith Charles, Spencer
Denison, Helena
Bernes, Michael Christopher
Chana, Slinder Thing
Genens, Lynn
Pilkington, Christopher John
Application Number:
JP2008534079A
Publication Date:
March 19, 2009
Filing Date:
October 09, 2006
Export Citation:
Assignee:
Arrow Therapeutics Limited
International Classes:
C07D239/94; A01N43/84; A01P1/00; A61K31/5377; A61K31/7056; A61K38/21; A61P1/16; A61P31/14
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita