セロトニン5-HT6受容体の調節に応答する障害の治療に好適なキノリン化合物

Japanese Patent JP5501230

B2

The present invention relates to novel quinoline compounds of the formula (I) and to the salts thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for treating diseases that respond to modulation of the serotonin 5-HT6 receptor. In formula (I) R is a moiety of the formula (R) wherein * indicates the binding site to the quinolinyl radical and wherein A, B, X', Y, Q, R1, R2, R3, R4, R5, m, n, p, q, Ra, Rb, X and Ar are as defined in claim 1.

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Turner, Sheen Colum
Braille, Billfleet
Haupt, Andreas
Lange, Udo
Dresser, carla
Bitsuke, Karsten
Unger, Liliane
Metzler, Mario
Bernett, Wolfgang
Mylar, matias

JP2010519460A

May 21, 2014

August 06, 2008

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ABBOTT LABORATORIES

C07D471/04; A61K31/407; A61K31/437; A61K31/4375; A61P1/04; A61P3/04; A61P3/10; A61P9/00; A61P11/00; A61P25/00; A61P25/02; A61P25/06; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P25/34; A61P35/00; A61P43/00; C07D487/04; C07D519/00

JP2005531518A
JP2007506704A
JP2002504484A
JP2007538045A
JP2007505075A
JP2008536950A
JP2007510642A
JP2008509099A

Kawaguchi International Patent Office
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura

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