Title:
4,5-DIHALOANILINE DERIVATIVE AND ITS PRODUCTION
Document Type and Number:
Japanese Patent JPH08283217
Kind Code:
A
Abstract:
PURPOSE: To obtain 3-fluoro-4-chloro-6-aminobenzaldehyde (acetal) as a new compound capable of giving quinolines having antiallergic activity in high yield, thus useful as an intermediate for antiallergic agents.
CONSTITUTION: This new compound is 3-fluoro-4-chloro-6-aminobenzaldehyde of formula I or a compound of formula II (R1 and R2 are each a 1-4C alkyl and may be bound to each other) (e.g. 3-fluoro-4-chloro-6-aminobenzaldehyde ethyleneacetal). The compound of formula I or formula II is obtained by catalyst hydrogen reduction of a compound of formula III [X1 is F; X2 is Cl; Y is formyl or an acetal group of the formula CH(OR1)(OR2)] in the presence of a platinum- or ruthenium-contg. catalyst in an organic solvent under pressure.
Inventors:
ATAKA KIKUO
YONEDA YASUHIRO
KONO MASAHIKO
YONEDA YASUHIRO
KONO MASAHIKO
Application Number:
JP8903695A
Publication Date:
October 29, 1996
Filing Date:
April 14, 1995
Export Citation:
Assignee:
UBE INDUSTRIES
International Classes:
B01J23/46; B01J27/045; C07B61/00; C07C213/02; C07C217/76; C07C221/00; C07C223/06; (IPC1-7): C07C223/06; B01J23/46; B01J27/045; C07C213/02; C07C217/76; C07C221/00