Title:
アミノアルコール誘導体
Document Type and Number:
Japanese Patent JP4618250
Kind Code:
B2
Abstract:
The present invention relates to a compound formula[I]: wherein X is bond, -CH2-, -O- or -NH-, R1 and R12 are each independently hydrogen, halogen, lower alkyl, etc., R2 is hydrogen or optionally substituted lower alkyl, R3 is hydrogen or an amino protective group, R4, R5 and R6 are each independently hydrogen or optionally substituted lower alkyl, R7 is -Z-R13, in which Z is bond, etc., and R13 is carboxy, lower alkoxycarbonyl, (lower alkylsulfonyl)carbamoyl or lower alkanoylsulfamoyl, R8 is -Y-R9, in which Y is bond, -CH2-, -O-, -S-, etc., and R9 is hydrogen, lower alkyl, cyclo(lower)alkyl, etc., and R11 is hydrogen, lower alkyl, lower alkoxy, etc., or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.
More Like This:
Inventors:
Koji Hattori
Toda Susumu
Masashi Imanishi
Shinji Ito
Kenichi Washizuka
Takeki Araki
Minoru Sakurai
Daisuke Tanabe
Toda Susumu
Masashi Imanishi
Shinji Ito
Kenichi Washizuka
Takeki Araki
Minoru Sakurai
Daisuke Tanabe
Application Number:
JP2006520478A
Publication Date:
January 26, 2011
Filing Date:
December 20, 2004
Export Citation:
Assignee:
Astellas Pharma Inc.
International Classes:
C07C311/51; A61K31/18; A61K31/195; A61K31/4406; A61P1/00; A61P1/04; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P13/00; A61P13/02; A61P13/08; A61P25/22; A61P25/24; A61P27/06; A61P29/00; A61P43/00; C07C229/38; C07C229/56; C07C271/16; C07C271/22; C07C311/06; C07C311/13; C07C321/28; C07C323/12; C07C323/52; C07C323/63; C07D213/28; C07D213/38; C07D213/61
Domestic Patent References:
JP2002518374A | ||||
JP3503405A | ||||
JP2005530852A | ||||
JP2005520501A | ||||
JP2005518448A | ||||
JP2005518357A |
Foreign References:
WO2004072016A1 |
Attorney, Agent or Firm:
Morita Taku
Emiko Yano
鈴木 ▲頼▼子
Hamai Kosuke
Emiko Yano
鈴木 ▲頼▼子
Hamai Kosuke