Title:
疼痛治療のための化合物
Document Type and Number:
Japanese Patent JP2006519823
Kind Code:
A
Abstract:
Compounds of the class of adenosines, represented by structural formula I, wherein R is C1-4 alkoxy, and X is H or OH, excluding 2-methoxyadenosine, are useful as analgesics, particularly in a method of preventing, treating, or ameliorating pain which comprises administering a compound of formula I to a subject in need of such prevention, treatment, or amelioration.
Inventors:
Peter Richardson
Kevin Lee
Lisa Lion
Kevin Lee
Lisa Lion
Application Number:
JP2006505920A
Publication Date:
August 31, 2006
Filing Date:
March 05, 2004
Export Citation:
Assignee:
Cambridge Biotechnology Ltd.
International Classes:
A61K31/7076; A61P1/00; A61P1/18; A61P3/10; A61P9/00; A61P9/10; A61P11/00; A61P15/00; A61P17/02; A61P19/00; A61P19/02; A61P19/06; A61P19/10; A61P21/00; A61P21/04; A61P25/00; A61P25/02; A61P25/04; A61P29/00; A61P31/18; A61P31/22; A61P35/00; A61P37/02; A61P43/00; C07H19/167; C07H19/16
Other References:
JPN6010009392, Ｅｕｒｏｐｅａｎ Ｊ． Ｐｈａｒｍａｃｏｌ．, 1989, １６２, ３６５−３６９
JPN6010009395, Ｅｕｒ． Ｊ． Ｍｅｄ． Ｃｈｅｍ．, 1997, ３２, ５０５−５１３
JPN5005012789, ＫＡＵＬ Ｐ, "ＡＤＥＮＯＳＩＮＥ ＡＧＯＮＩＳＴ ＯＦ ＭＡＲＩＮＥ ＯＲＩＧＩＮ ＩＮＤＩＣＡＴＩＶＥ ＯＦ ＴＷＯ ＴＹＰＥＳ ＯＦ ＡＤＥＮＯＳＩＮＥＲＧＩＣ ＲＥＣＥＰＴＯＲＳ", Ｐｈａｒｍａｃｏｌｏｇｉｓｔ, 1981, Ｖ２３ Ｎ３, Ｐ．ＮＯ．５４０
JPN5005012787, ＢＥＬＦＲＡＧＥ ＭＡＮＳ, ＡＮＥＳＴＨＥＳＩＡ ＡＮＤ ＡＮＡＬＧＥＳＩＡ, 199907, Ｖ８９ Ｎ１, Ｐ１３６−１４２
JPN6010009397, Ｅｕｒｏｐｅａｎ Ｊ． Ｐｈａｒｍａｃｏｌ．, 1998, ３４７, １−１１
JPN6010009395, Ｅｕｒ． Ｊ． Ｍｅｄ． Ｃｈｅｍ．, 1997, ３２, ５０５−５１３
JPN5005012789, ＫＡＵＬ Ｐ, "ＡＤＥＮＯＳＩＮＥ ＡＧＯＮＩＳＴ ＯＦ ＭＡＲＩＮＥ ＯＲＩＧＩＮ ＩＮＤＩＣＡＴＩＶＥ ＯＦ ＴＷＯ ＴＹＰＥＳ ＯＦ ＡＤＥＮＯＳＩＮＥＲＧＩＣ ＲＥＣＥＰＴＯＲＳ", Ｐｈａｒｍａｃｏｌｏｇｉｓｔ, 1981, Ｖ２３ Ｎ３, Ｐ．ＮＯ．５４０
JPN5005012787, ＢＥＬＦＲＡＧＥ ＭＡＮＳ, ＡＮＥＳＴＨＥＳＩＡ ＡＮＤ ＡＮＡＬＧＥＳＩＡ, 199907, Ｖ８９ Ｎ１, Ｐ１３６−１４２
JPN6010009397, Ｅｕｒｏｐｅａｎ Ｊ． Ｐｈａｒｍａｃｏｌ．, 1998, ３４７, １−１１
Attorney, Agent or Firm:
Mitsuo Tanaka
Tadayuki Motoyama
Kenji Tomita
Tadayuki Motoyama
Kenji Tomita