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Title:
シクロヘキシルアミン類
Document Type and Number:
Japanese Patent JP6495654
Kind Code:
B2
Abstract:
The present application provides novel compounds and methods for preparing and using these compounds. These compounds are useful in treating pain, itch, overactive bladder and/or interstitial cystitis in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) and a TRPV1 receptor activator. In one embodiment, the TRPV1 receptor activator is lidocaine.

Inventors:
Scott Kevin Thompson
Roger Astbury Smith
Sandeep Gupta
Tony Priestley
Nicholas James Laping
Assis K. Saha
Sonali Rudra
Application Number:
JP2014538934A
Publication Date:
April 03, 2019
Filing Date:
October 24, 2012
Export Citation:
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Assignee:
Asana Biosciences, Limited Liability Company
International Classes:
A61K31/167; C07C219/14; A61K31/235; A61K31/351; A61K31/381; A61K31/40; A61K31/4025; A61K31/452; A61K31/4535; A61K45/00; A61P13/10; A61P17/04; A61P25/04; A61P43/00; C07D207/34; C07D295/088; C07D309/14; C07D333/38; C07D333/70
Domestic Patent References:
JP472623B1
Other References:
Acta Pharm.Suec.,(1984),Vol.21,No.5,pp.271-294
Cellular and Molecular Basis of Cholinergic Function (1987),pp.347-354
IZVESTIYA AKADEMII NAUK ARMYANSKOI SSR,KHIMICHESKIE NAUKI,(1963),16(2),pp.163-174
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei