EXPRESSION OF XENOGENEIC (HUMAN) IMMUNOGLOBULIN IN CLONED, TRANSGENIC UNGULATE

Title:

EXPRESSION OF XENOGENEIC (HUMAN) IMMUNOGLOBULIN IN CLONED, TRANSGENIC UNGULATE

Document Type and Number:

Japanese Patent JP2005224250

Kind Code:

A

Abstract:

To provide transgenic ungulates deceased in expression of its endogenous antibodies.

The ungulates containing mutation decreasing expression of endogenous antibodies on a gene encoding the endogenous antibodies, or containing a promotor decreasing expression of endogenous antibodies by functionally bonding the promotor to a gene encoding the endogenous antibodies are provided.

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Inventors:

ROBL JAMES M
GOLDSBY RICHARD A
FERGUSON STACY E
KUROIWA YOSHIMI
TOMIZUKA KAZUMA
ISHIDA ISAO

Application Number:

JP2005136675A

Publication Date:

August 25, 2005

Filing Date:

May 09, 2005

Export Citation:

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Assignee:

HEMATECH LLC
KIRIN BREWERY

International Classes:

A01K67/027; C07K14/47; C07K16/04; C07K16/18; C12N5/10; C12N9/10; C12N15/02; C12N15/09; C12N15/85; C12P21/08; (IPC1-7): A01K67/027; C12N5/10; C12N15/09

Attorney, Agent or Firm:

Yusuke Hiraki
Ishii Teiji
Satoshi Fujita

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