抗発作治療用のGABA及びL-グルタミン酸類縁体

Title:

抗発作治療用のGABA及びL-グルタミン酸類縁体

Document Type and Number:

Japanese Patent JP4297814

Kind Code:

B2

Abstract:

A compound of formula (I) wherein R1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R2 is hydrogen or methyl; and R3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are also disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are further disclosed.

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Inventors:

Richard B Silverman
Liszard Andruskie Wyck
Po Y You
Dennis Martin Sovier Lei
Lloyd Charles Franklin
Mark allen shwind

Application Number:

JP2004075406A

Publication Date:

July 15, 2009

Filing Date:

March 16, 2004

Export Citation:

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Assignee:

Northwestern University

International Classes:

A61P9/10; A61K31/195; C07C229/08; A61K31/197; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/28; C07B53/00; C07B61/00; C07C53/42; C07C69/34; C07C69/347; C07C69/40; C07C69/675; C07C69/96; C07C227/06; C07C227/12; C07C227/32; C07C229/00; C07C229/06; C07C229/10; C07C229/24; C07C229/36; C07C247/12; C07C309/30; C07C309/73; C07C317/44; C07D263/22; C07D263/26

Domestic Patent References:

JP62230757A
JP3856816B2

Attorney, Agent or Firm:

Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita

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