IMMUNOGENIC HYBRID OprF-OprI DERIVED FROM PSEUDOMONAS AERUGINOSA MEMBRANE PROTEIN

Japanese Patent JP3762779

B2

PROBLEM TO BE SOLVED: To provide a hybrid protein and an antibody directed to the hybrid protein, both capable of conferring protection against an infection by Pseudomonas aeruginosa to a laboratory animal or man.
SOLUTION: The hybrid protein comprises Pseudomonas aeruginosa outer membrane protein I (OprI) an amino terminal end of which is fused to the carboxy terminal end of a carboxy terminal portion in the Pseudomonas aeruginosa outer membrane protein F (OprF). A monoclonal or polyclonal antibody against the hybrid protein is also provided.

JPH0866198	EPITOPIC REGION OF PNEUMOCOCCAL SURFACE PROTEIN A
WO/2021/118922	CAR T CELLS THAT TARGET ASPERGILLUS ASSOCIATED ANTIGENS
WO/2022/055408	DESLORATADINE OR LORATADINE FOR USE IN THE TREATMENT OF BREAST CANCER

Bernhard and Knap
Claus-Dieter, Hungeller
Michael, Brecker
Bernd, Ulrich, von, Specht
Horst, domday

JP2004363728A

April 05, 2006

December 15, 2004

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Chiron Bering Gamebha and Company

A61K39/00; C12N15/09; A61K39/104; A61K39/395; A61P31/04; C07H21/04; C07K1/22; C07K14/195; C07K14/21; C07K14/41; C07K14/705; C07K16/00; C07K16/12; C07K19/00; C12N15/02; C12N15/31; C12P21/02; C12P21/04; C12P21/08; G01N33/569; G01N33/577; C12R1/19; C12R1/91; (IPC1-7): C07K14/21; A61K39/00; A61K39/104; A61P31/04; C07K16/12; C07K19/00; C12N15/09

JP64085086A
JP2163088A

Infection and Immunity,1988年,Vol. 56,p. 1017-1022
Infection and Immunity,1990年,Vol. 58,p. 2241-2244
Behring Inst. Mitt,1994年,No. 95,p. 85-96
Infection and Immunity,1995年,Vol. 63,p. 1855-1862
Infection and Immunity,1995年,Vol. 63,p. 38-42

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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